四种诊断血吸虫病方法的比较研究

本文对血吸虫病监测中的COPT、IHA、PVC-IEST和F-ELISA4种血清免疫诊断方法进行了比较.4种方法的敏感性依次为70.45%、65.91%、54.55%、68.18%,假阳性率均不超过5.00%,4种方法的操作时间和劳动强度以COPT为最长、最大,其余3种方法较为接近,成本费用以IHA最低.作者认为,在血吸虫病巩固监测地区,可用IHA和F-ELISA法结合门诊肝功能血清检查进行监测,有史者加做COPT,阳性者可作病人处理.疫区暂住人员监测可用PVC-IEST和IHA检测,两种方法均阳性者可作病人处理.

STUDY IN COMPARISON OF 4 METHODS IN DIAGNOSIS OF SCHISTOSOMIASIS

4 sero-immuno diagnostic methods,COPT,IHA,PVC-IEST and F-ELISA,were used in schistosomiasis surveillance. The respective sensitivity of these methods was 70.45%? 65. 91%?54. 55% and 68.18%,while the false positive rate was below 5% in all methods. A-mong these methods;COPT took more time and was more strenous to accomplish. The cost of IHA was the lowest of all. The authors suggested that for surveillance in controlled areas, when liver faction test was examined in O. P. D. patients,IHA or F-ELISA could be tested by the same time in order to fined out more schistosomiasis patient. In previously infected persons,COPT might be added and those with positive results should be considered as patients. For temporary inhabitants from endemic areas,PVC-IEST or IHA could be used and those with positive results should be considered as infected persons.