特发性肺纤维化急性加重期高分辨率CT影像学特点

目的了解特发性肺间质纤维化(IPF)急性加重期高分辨率CT(HRCT)影像学特点。方法回顾性分析6例IPF急性加重期患者的HRCT影像学改变,总结其特点。结果IPF的HRCT影像学改变多样,可表现为双肺多灶性病变、磨玻璃影、网状影、蜂窝状影、细支气管扩张、胸膜下线、支气管血管束增粗以及肺气肿。急性加重期HRCT特点为双肺出现新增磨玻璃影,与双侧胸膜下网格状影及蜂窝状影重叠。结论IPF急性加重期HRCT影像学表现具有一定特征性,HRCT对IPF的诊断及急性加重的判断具有重要意义。

Acute Exacerbation of Idiopathic Pulmonary Fibrosis: Imaging Characteristics under High Resolution Computed Tomography

Objective To explore the imaging features of acute exacerbation of idiopathic pulmonary fibrosis （IPF） under high-resolution computed tomography （HRCT）. Methods The HRCT imaging features of six patients who met the criteria for acute exacerbation of IPF were analyzed retrospectively. Results The manifestations of IPF on HRCT scan were various in forms and distribution, as multifoeal, ground-glass opacity, reticular shadow, honeycombing densities, capillary hronchiectasis, subpleural lines, traction bronehiolectasis and emphysema. The characteristic lesions were newly diffuse bilateral ground-glass opacity at the time of acute exacerbation, superimposed on subpleural reticular and honeycombing densities. Conclusions Chest HRCT findings in acute exacerbation of IPF are characteristic. HRCT is accurate and superior in diagnosis of IPF and in determining acute exacerbation of IPF.