中国18岁及以上人群血脂异常流行特点研究

目的 掌握我国城乡及不同地区居民血脂异常及高胆固醇血症、高甘油三酯血症、低高密度脂蛋白血症流行情况及其差异。方法 调查时间为2002年8至12月。采用酶法对49252名调查对象空腹血浆总胆固醇、甘油三酯、高密度脂蛋白胆固醇进行测定。结果 按年龄和地区调整后,我国18岁及以上成人血脂异常患病率为18．6％,18-44岁、45-59岁和≥60岁人群的患病率分别为17．0％、22．9％和23．4％;男性为22．2％,女性为15．9％;城市为21．0％,农村为17．7％。我国18岁及以上成人高胆固醇血症患病率为2．9％,胆固醇边缘性升高率为3．9％;高甘油三酯血症患病率为11．9％;低高密度脂蛋白血症患病率为7．4％。结论 血脂异常已成为威胁我国人民健康的重要危险因素;18岁及以上人群血脂异常以高甘油三酯、低高密度脂蛋白胆固醇血症为主;中、老年人血脂异常患病率相近,城乡差别不大。作好人群早期综合防治工作十分重要。

Epidemiologic characteristics of dyslipidemia in people aged 18 years and over in China

Objective To study the difference in prevalence of dyslipidemia, hypercholesterolemia, hypertriglyceridemia and low blood high-density lipoprotein cholesterol (HDL-C) between the residents of urban and rural areas of varied regions in China.Methods Fasting plasma levels of total cholesterol, triglyceride and HDL-C were determined with the enzyme methods for 49 252 subjects aged 18 and over during August to December, 2002.Results Prevalence of dyslipidemia in Chinese adults aged 18 and over was 18.6%, with 17.0%, 22.9% and 23.4% in the groups of 18-44, 45-59 and over 60 years old, respectively, 22.2% and 15.9% in males and females, respectively, and 21.0% and 17.7% in urban and rural areas, respectively. Prevalence of hypercholesterolemia, hypertriglyceridemia and low blood HDL-C in those aged 18 and over was 2.9%, 11.9% and 7.4%, respectively.Conclusions Dyslipidemia has become one of important risk factors threatening health of Chinese people, with hypertriglyceridemia and low blood HDL-C as two major types in those aged 18 and over. Prevalence of dyslipidemia was nearly the same in the middle-aged and in the elderly people, and not significantly different in those living in urban areas from those in rural areas. It is very important to pay more attention to earlier comprehensive prevention and control of dyslipidemia.