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Effect of type I collagen on the adhesion, proliferation, and osteoblastic gene expression of bone marrow-derived mesenchymal stem cells
引用本文:刘刚,胡蕴玉,赵建宁,吴苏稼,熊卓,吕荣. Effect of type I collagen on the adhesion, proliferation, and osteoblastic gene expression of bone marrow-derived mesenchymal stem cells[J]. 中华创伤杂志(英文版), 2004, 7(6): 358-362
作者姓名:刘刚  胡蕴玉  赵建宁  吴苏稼  熊卓  吕荣
作者单位:Department of Orthopedics,Nanjing General Hospital,Nanjing Military District,Nanjing,Jiangsu 210001,China,Institute of Orthopedics of Xijing Hospital,Fourth Military Medicical University,Xi'an,Shanxi,China,Department of Orthopedics,Nanjing General Hospital,Nanjing Military District,Nanjing,Jiangsu 210001,China,Department of Orthopedics,Nanjing General Hospital,Nanjing Military District,Nanjing,Jiangsu 210001,China,Department of Mechanical Engineering of Tsinghua University,Beijing,China,Institute of Orthopedics of Xijing Hospital,Fourth Military Medicical University,Xi'an,Shanxi,China
基金项目:TheNinthFive YearPlanProjectonNewMaterialintheStateHi TechPlan (0 0 9 0 16 0 ),KeySubjectfundedbytheArmyMedicamentandHealthScientificSearchFund,No .0 1Z0 79
摘    要:tificially synthesizedpolymericproductssuchaspolylactide (PLA ) ,polyglycolide (PGA ) ,andtheircopolymersarefrequently usedtissueengineeringmatrixsubstitutivematerials .Unfortunately ,theirapplicationisseriouslyrestrictedfortheirpoorhydrophilicproperty ,weakcelladsorptionforces ,anddifficultyininteractionwithcells .1,2 ThisstudyintendstoevaluatethecapacityofcollagenIinpromotingadhesion ,proliferation ,anddifferentiationofMSCs ,tolayanexperimentalbasisforbonytissueengineering .METHODSPrep…

关 键 词:间叶细胞 干细胞 骨髓 细胞粘附力 PLGA OPN RNA ALP MSC RT-PCR

Effect of type I collagen on the adhesion, proliferation, and osteoblastic gene expression of bone marrow-derived mesenchymal stem cells
Gang Liu,Yun-Yu Hu,Jian-Ning Zhao,Su-Jia Wu,Zhuo Xiong,Rong Lu. Effect of type I collagen on the adhesion, proliferation, and osteoblastic gene expression of bone marrow-derived mesenchymal stem cells[J]. Chinese journal of traumatology, 2004, 7(6): 358-362
Authors:Gang Liu  Yun-Yu Hu  Jian-Ning Zhao  Su-Jia Wu  Zhuo Xiong  Rong Lu
Affiliation:1. Department of Orthopedics, Nanjing General Hospital, Nanjing Military District, Nanjing, Jiangsu,210001, China
2. Institute of Orthopedics of Xijing Hospital, Fourth Military Medicical University, Xi'an, Shanxi, China
3. Department of Mechanical Engineering of Tsinghua University, Beijing, China
Abstract:
Keywords:Mesenchymal stem cells  Collagen,type-Ⅰ  Cell adhesion
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