Immunological memory in CBA and CBA/N mice after vaccination with Mycobacterium bovis (BCG) |
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| Authors: | Nikonenko B V Khaidukov S V Litvinov I S Bocharova Apt A S |
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| Affiliation: | (1) Central Institute of Tuberculosis, Russian Academy of Medical Science, Russia;(2) M. M. Shemyakin and Yu. V. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow |
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| Abstract: | In inbred CBA and CBA/N mice immunological memory was induced by subcutaneous injection of Mycobacterium bovis (BCG). Experiments with adoptive transfer of spleen T cells and ionomycin-resistant T cells (memory cells) between CBA and CBA/N mice in various combinations showed that immunological memory was not formed in CBA/N mice, but can be induced by adoptive transfer of cells from CBA mice. |
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| Keywords: | immune memory tuberculosis adoptive transfer |
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