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Epidemiology and clinical and pathologic characteristics of cutaneous malignant melanoma in Abruzzo (Italy) |
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| Authors: | Paolo Amerio MD PhD Lamberto Manzoli MD PhD Matteo Auriemma MD Angelo Carbone MD PhD Gianluca Proietto MD Domenico Angelucci MD Antonello Tulli MD |
| Affiliation: | From the Departments of Dermatology and Pathology, and Section of Epidemiology and Public Health, G. D'Annunzio University, Chieti, and Department of Dermatology, Catholic University of the Sacred Heart, Rome, Italy |
| Abstract: | Background Malignant melanoma incidence has increased worldwide in recent decades. Cancer registry-derived epidemiologic data on malignant melanoma in Italy are available only in some northern regions of the country. Aim To report the number and characteristics of incident cases of cutaneous malignant melanoma in Abruzzo, a central-southern Italian region. Methods Screening of the archives of the pathology departments of regional hospitals from 2002 to 2005 was performed. For each patient, clinical and pathologic data were collected. Cases of metastatic, multiple, or relapsing melanoma were excluded. Results Six hundred and seventy-two cases of primary melanoma were recorded, with an incidence rate of 14.1 per 100,000 inhabitants per year. Differences related to gender (41.1% males and 58.9% females) and age (35% in the 50–70-year age group) were found. The trunk (30.7%) and lower limbs (25.94%) were the most frequent sites observed. The superficial spreading histiotype and thin melanoma (≤ 1.00 mm) were more often recorded (44.8% and 62%, respectively). Conclusions Despite the bias present in this study, linked to the nature and source of the data, we believe that the figures found in this report are comparable with those obtained in the international literature from other Mediterranean countries. |
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