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补阳还五汤提取物对家兔高胆固醇血症和血液流变性影响的实验研究
引用本文:毛小平,谢忠明.补阳还五汤提取物对家兔高胆固醇血症和血液流变性影响的实验研究[J].微循环学杂志,2001,11(4):19-20.
作者姓名:毛小平  谢忠明
作者单位:1. 武汉大学人民医院神经科,武汉,430060
2. 武汉大学人民医院检验科,武汉,430060
基金项目:湖北省教委重点课题基金资助(96A020)
摘    要:目的 :观察补阳还五汤提取物对高胆固醇血症和血液流变性的影响。方法 :采用高胆固醇饲料喂养家兔法复制高胆固醇血症模型 ,观察补阳还五汤提取物 (BDE)对TCh、TG和血液流变学的影响。结果 :BDE处理的兔TCh、TG显著降低 (P <0 .0 1) ,全血表观粘度(低切 10s- 1 )、红细胞聚集指数 (EAI)均显著降低 (P <0 .0 1)。结论 :补阳还五汤提取物能有效降低TCh、TG和改善血液流变性。

关 键 词:补阳还五汤提取物  高胆固醇血症  血液流变学
修稿时间:2001年5月22日

Influences of Buyanghuanwu Decoction Extact on Hypercholesterolemia and Hemorheolog-ical Property in Rabbits
Mao Xiaoping,Xie Zhongming/Renmin Hospital of Wuhan University,Wuhan.Influences of Buyanghuanwu Decoction Extact on Hypercholesterolemia and Hemorheolog-ical Property in Rabbits[J].Chinese Journal of Microcirculation,2001,11(4):19-20.
Authors:Mao Xiaoping  Xie Zhongming/Renmin Hospital of Wuhan University  Wuhan
Institution:Mao Xiaoping,Xie Zhongming/Renmin Hospital of Wuhan University,Wuhan 430060
Abstract:Objective: To investigate the effects of Buyanghuanwu Decoction Extact(BDE) on hypercholesterolemia and hemorheological property.Method: The model of hypercholesterolemia with rabbits was fed with cholesterol powder;The effect of BDE on TCh,TG and the indexes of hemorheology was observed.Results: TCh and TG of rabbits treated with BDE were significantly decreased(P<0.01);low share rate blood apparent viscosity and erythrocyte aggregation index all significantly decreased too(P<0.01).Conclusion: These suggest that BDE can decrease TCh,TG and improve hemorheological property.
Keywords:Buyanghuanwu decoction extact  Hypercholesterolemia  Hemorheology
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