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2008年北京医院细菌耐药性监测结果
引用本文:艾效曼,陶凤蓉,宣天芝,许宏涛,陈东科,胡云建. 2008年北京医院细菌耐药性监测结果[J]. 中国感染与化疗杂志, 2010, 10(2): 134-138
作者姓名:艾效曼  陶凤蓉  宣天芝  许宏涛  陈东科  胡云建
作者单位:卫生部北京医院检验科;
基金项目:卫生部北京医院青年基金BJ-2008-70
摘    要:目的了解2008年我院临床分离菌对常用抗菌药物的耐药性。方法采用Kirby-Bauer法对我院2008年临床分离菌2538株进行药敏试验,WHONET5.4统计软件对数据进行分析。结果革兰阴性杆菌中铜绿假单胞菌456株(18.0%)、大肠埃希菌336株(13.2%)和嗜麦芽窄食单胞菌218株(11.0%);革兰阳性球菌中,金葡菌280株(11.0%)、肠球菌属163株(6.4%)和凝固酶阴性葡萄球菌(CNS)142株(5.6%)。药敏试验结果显示β溶血性链球菌中未见青霉素耐药菌株。流感嗜血杆菌产β内酰胺酶株占15.4%。MRSA和MRCNS分别占金葡菌和CNS的76.7%(215/280)和69.0%(98/142)。发现5株耐万古霉素粪肠球菌和18株耐万古霉素屎肠球菌。大肠埃希菌产ESBLs率为52.7%,肺炎克雷伯菌为24.8%,铜绿假单胞菌和鲍曼不动杆菌中已分别检出2.0%(9/456)和13.0%(17/131)的泛耐药菌株。结论定期进行耐药性监测有助于了解我院细菌耐药性变迁,为临床经验用药提供依据。

关 键 词:耐药性监测  抗菌药  药敏试验  

Surveillance of bacterial resistance in Beijing Hospital during year 2008
AI Xiaoman,TAO Fengrong,XUAN Tianzhi,XU Hongtao,CHEN Dongke,HU yunjian.. Surveillance of bacterial resistance in Beijing Hospital during year 2008[J]. Chinese Journal of Infection and Chemotherapy, 2010, 10(2): 134-138
Authors:AI Xiaoman  TAO Fengrong  XUAN Tianzhi  XU Hongtao  CHEN Dongke  HU yunjian.
Affiliation:Department of Laboratory Medicine/a>;Beijing Hospital/a>;Beijing 100730/a>;China
Abstract:Objective To investigate the antibiotic resistance of clinical isolates collected from Beijing Hospital in 2008.Methods Kirby-Bauer method was used to test the susceptibility of 2 538 clinical isolates to selected antimicrobial agents.The susceptibility data were analyzed using WHONET software.Results The most frequently isolated gram negative bacilli were P.aeruginosa(456,18.0%),E.coli(336,14.6%),S.maltophilia(218,11.3%).The most common gram positive cocci were S.aureus(280,8.6%),Enterococcus spp.(163,6.4%...
Keywords:surveillance of bacterial resistance  antimicrobial agent  bacterial susceptibility testing  
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