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羟基喜树碱膀胱内灌注预防浅表性膀胱癌术后复发
引用本文:王立国,方青,刘建平,王凤华.羟基喜树碱膀胱内灌注预防浅表性膀胱癌术后复发[J].吉林医药学院学报,2003,25(2):92-93.
作者姓名:王立国  方青  刘建平  王凤华
作者单位:1. 第四军医大学吉林军医学院附属医院泌尿外科,吉林,吉林,132013
2. 第四军医大学吉林军医学院病理学教研室,吉林,吉林,132013
摘    要:目的 探讨应用羟基喜树碱 (HCPT)进行膀胱内灌注 ,预防浅表性膀胱癌术后复发的疗效和安全性。方法 对保留膀胱手术治疗后的 89例浅表性膀胱癌患者 ,采用HCPT(10mg 2 0ml)进行膀胱内灌注治疗。结果 经平均随访 2 7.9个月 ,89例患者中复发 19例 (2 1.3% ) ,且并发症和副作用较小。结论 HCPT膀胱内灌注预防浅表性膀胱癌术后复发 ,具有较好的效果 ,毒副作用少而轻

关 键 词:膀胱癌  膀胱灌注  术后复发
文章编号:1009-8488(2003)02-0092-02
修稿时间:2002年10月26

Prevention of postoperative relapse of superficial carcinoma of urinary bladder through perfusion of hydroxycamptothecine into urinary bladder
WANG Li guo ,FANG Qing ,LIU Jian ping ,WANG Feng hua.Prevention of postoperative relapse of superficial carcinoma of urinary bladder through perfusion of hydroxycamptothecine into urinary bladder[J].Journal of Jilin Medical College,2003,25(2):92-93.
Authors:WANG Li guo  FANG Qing  LIU Jian ping  WANG Feng hua
Institution:WANG Li guo 1,FANG Qing 2,LIU Jian ping 1,WANG Feng hua 1
Abstract:Objective To explore the therapeutic effect and safety of prevention of postoperative relapse of superficial carcinoma of urinary bladder through perfusion of hydroxycamptothecine into urinary bladder.Methods HCPT(10 mg/ 20 ml) was used in urinary bladder perfusion for 89 cases with superficial carcinoma of urinary bladder ,whose urinary bladders were retained for operative treatment.Results Through the follow up visit of 27.9 months by average,relapse was found in 19 cases (21.3 %) with little complication and side effect.Conclusion This method has a good effect with less side effect.
Keywords:carcinoma of urinary bladder  urinary  bladder perfusion  postoperative relapse
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