| 银耳多糖对实验性2型糖尿病大鼠血糖及血脂的影响 |
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| 引用本文： | 田春雨,薄海美,李继安.银耳多糖对实验性2型糖尿病大鼠血糖及血脂的影响[J].辽宁中医杂志,2011(5):986-987. |
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| 作者姓名： | 田春雨 薄海美 李继安 |
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| 作者单位： | 河北联合大学; |
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| 基金项目： | 国家科技部国际科技合作项目(2008DFA31050) |
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| 摘 要： | 目的:观察银耳多糖对链脲佐菌素(STZ)和高能量饲料诱发的2型糖尿病模型大鼠血糖、血脂的影响。方法:取Wister雄性大鼠65只,随机分为正常组、糖尿病和模型对照组、银耳多糖低中高剂量治疗组及罗格列酮治疗组,除正常组外,其他各组均采用高能量饮食4周后小剂量腹腔注射STZ的方法建立2型糖尿病大鼠模型。持续给药8周后测空腹血糖、血脂的含量。结果:采用高能量饮食加STZ诱发的2型糖尿病大鼠空腹血糖、血清TG(甘油三酯)、TCH(总胆固醇)、LDL(低密度脂蛋白)水平明显高于正常对照组(P<0.05),HDL(高密度脂蛋白)明显下降(P<0.05);银耳多糖可降低2型糖尿病模型大鼠的血糖、TG、TCH及LDL水平,升高HDL水平,与模型组比较有明显改善(P<0.05),与罗格列酮药物治疗组无显著性差异(P>0.05)。结论:银耳多糖能有效地降低2型糖尿病模型大鼠的血糖,调节血脂。
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| 关 键 词： | 银耳多糖 2型糖尿病 血糖 血脂 |
The Influence of Tremella Polysaccharide on Blood Glucose and Serum Lipoprotein In Experimental Type 2 Diabetic Rats |
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| TIAN Chun-yu,BO Hai-mei,LI Ji-an.The Influence of Tremella Polysaccharide on Blood Glucose and Serum Lipoprotein In Experimental Type 2 Diabetic Rats[J].Liaoning Journal of Traditional Chinese Medicine,2011(5):986-987. |
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| Authors: | TIAN Chun-yu BO Hai-mei LI Ji-an |
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| Institution: | TIAN Chun-yu,BO Hai-mei,LI Ji-an(Hebei United University,Tangshan 063000,Hebei,China) |
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| Abstract: | Objective:To observe the influence of Tremella Polysaccharide(TP) on blood glucose,serum lipoprotein in diabetic rats induced by streptozotocin(STZ) and high-energy diet. Methods:All rats were randomly divided into six groups:normal blank group,model group,TP low and middle and high dose treatment group,rosiglitazone treatment group.Besides blank control group,others were established as type 2 diabetes model by high-energy diet for 4 weeks and lower dose injected with intraperitoneal STZ.Blood glucose,serum... |
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| Keywords: | Tremella Polysaccharide(TP) Type 2 Diabetes Mellitus(T2DM) Blood Glucose Serum Lipoprotein |
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