双镜联合治疗胃间质瘤的预后及安全性分析

目的分析双镜联合治疗胃间质瘤的预后及安全性。方法回顾性队列研究2014年3月至2017年10月119例胃间质瘤患者临床资料,根据术式不同分为联合组(n=56例,胃镜联合腹腔镜)、腹腔镜组(n=63例)。采用SPSS 23.0软件进行数据处理,围手术期指标等计量资料以(x±s)表示,采用独立样本t检验;术后恶性潜能分级、核分裂像、并发症发生率采用χ² 检验;生存率采用Kaplan-meier法检验。P<0.05为差异有统计学意义。结果联合组手术时间、术中出血量比腹腔镜组低(P<0.05);联合组术后并发症总发生率(3.6%)比腹腔镜组(15.9%)低(P<0.05);两组患者术后首次排气时间、首次排便时间、住院时间、术后恶性潜能分级及核分裂像结果、术后2年生存率相比,差异均无统计学意义(P>0.05)o结论腹腔镜及双镜联合切除胃间质瘤,患者术后生存率相当,但双镜联合治疗胃间质瘤具有快速定位、出血量少、手术时间短、并发症少等优势。

Prognosis and safety analysis of double mirror combined therapy for gastric stromal tumor

Objective To analyze the prognosis and safety of dual-scopy combined treatment of gastric stromal tumors.Methods The clinical data of 119 patients with gastric stromal tumors from March 2014 to October 2017 were retrospectively analyzed.The patients were divided into combined group(n=56 cases,Gastroscope combined with laparoscopy)and laparoscopy group(n=63 cases).SPSS23.0 software was used for data processing.Perioperative indicators were expressed as(x±s),independent t-test was used.Postoperative malignant potential classification,mitotic figures,and complication rate were tested by χ² test.The survival rate was tested by Kaplan-meier method.P<0.05 was considered statistically significant.Results The operation time and intraoperative blood loss in the combined group were lower than those in the laparoscopic group(P<0.05);the total incidence of postoperative complications in the combined group(3.6%)was lower than that in the laparoscopic group(15.9%)(P<0.05);There were no significant differences in the first postoperative exhaust time,first defecation time,hospitalization time,postoperative malignant potential classification,results of mitotic figures and 2-year survival rate between the two groups(P>0.05).Conclusion The postoperative survival rate of patients with gastric stromal tumor is similar to that of patients with laparoscopic and dual endoscopic combined treatment.However,the dual endoscopic combined treatment of gastric stromal tumor has the advantages of rapid localization,less blood loss,short operation time and fewer complications.