High Frequency and Intensity Rehabilitation in 641 Subacute Ischemic Stroke Patients |
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Authors: | József Tollár Ferenc Nagy Bence Csutorás Nándor Prontvai Zsófia Nagy Katalin Török Eszter Blényesi Zsolt Vajda Dóra Farkas Béla E. Tóth Imre Repa Mariann Moizs Dávid Sipos András Kedves Árpád Kovács Tibor Hortobágyi |
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Affiliation: | 1. Somogy County Móricz Kaposi Teaching Hospital, Kaposvár, Hungary;2. University of Pécs, Faculty of Health Sciences, Doctoral School of Health Sciences, Pécs, Hungary;3. Dr József Baka Diagnostical, Oncoradiological, Research and Educational Center, Kaposvár, Hungary;4. Department of Pharmaceutical Surveillance and Economics, Faculty of Pharmacy, University of Debrecen, Debrecen, Hungary;5. Department of Oncoradiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary;6. University of Groningen, University Medical Center, Groningen, The Netherlands |
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Abstract: | ObjectivesTo determine the effects of exergaming on quality of life (QoL), motor, and clinical symptoms in subacute stroke patients.DesignA pseudorandomized controlled trial, using a before-after test design.SettingUniversity hospital.ParticipantsSubacute, ischemic stroke outpatients (N=3857), 680 of whom were randomized and 641 completed the study.InterventionsWe determined the effects of 5 times a week twice daily (EX2; 50 sessions; n=286) and once daily (EX1; 25 sessions; n=272) exergaming and low-intensity standard care (control [CON]; 25 sessions; n=83) on clinical, mobility, blood pressure (BP), and QoL outcomes.Main Outcome MeasuresThe primary outcome was Modified Rankin Scale. Secondary outcomes were activities of daily living, 5 aspects of health-related QoL, Beck Depression Inventory, 6-minute walk test (6MWT), Berg Balance Scale (BBS), and static balance (center of pressure).ResultsDuring exercise, the peak heart rate was 134, 134, and 126 beats per minute in the EX2, EX1, and CON groups, respectively. mRS improved similarly in the EX2 (–1.8; effect size, d=–4.0) and EX1 (–1.4; d=–2.6) groups, but more than in the CON group (–0.7; d=–0.6). QoL, Barthel Index, BBS, 6MWT, and standing posturography improved more in the EX2 group and the same in the EX1 and CON groups. Systolic and diastolic resting BP decreased more in the EX2 and EX1 groups than in the CON group. The intervention effects did not differ between men (n=349) and women (n=292).ConclusionsTwice daily compared with once daily high-intensity exergaming or once daily lower intensity standard care produced superior effects on clinical and motor symptoms, BP, and QoL in male and female subacute ischemic stroke participants. |
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Keywords: | Activities of daily living Exercise Quality of life Rehabilitation Virtual reality 6MWT" },{" #name" :" keyword" ," $" :{" id" :" kwrd0040" }," $$" :[{" #name" :" text" ," _" :" 6-minute walk test ADL" },{" #name" :" keyword" ," $" :{" id" :" kwrd0050" }," $$" :[{" #name" :" text" ," _" :" activities of daily living BBS" },{" #name" :" keyword" ," $" :{" id" :" kwrd0060" }," $$" :[{" #name" :" text" ," _" :" Berg Balance Scale BI" },{" #name" :" keyword" ," $" :{" id" :" kwrd0070" }," $$" :[{" #name" :" text" ," _" :" Barthel Index BP" },{" #name" :" keyword" ," $" :{" id" :" kwrd0080" }," $$" :[{" #name" :" text" ," _" :" blood pressure CON" },{" #name" :" keyword" ," $" :{" id" :" kwrd0090" }," $$" :[{" #name" :" text" ," _" :" control group COP" },{" #name" :" keyword" ," $" :{" id" :" kwrd0100" }," $$" :[{" #name" :" text" ," _" :" center of pressure EQ5-VAS" },{" #name" :" keyword" ," $" :{" id" :" kwrd0110" }," $$" :[{" #name" :" text" ," _" :" 100 mm visual analog measure of health-related quality of life EX1" },{" #name" :" keyword" ," $" :{" id" :" kwrd0120" }," $$" :[{" #name" :" text" ," _" :" 1 exergaming session daily EX2" },{" #name" :" keyword" ," $" :{" id" :" kwrd0130" }," $$" :[{" #name" :" text" ," _" :" 2 exergaming sessions daily HR" },{" #name" :" keyword" ," $" :{" id" :" kwrd0140" }," $$" :[{" #name" :" text" ," _" :" heart rate mRS" },{" #name" :" keyword" ," $" :{" id" :" kwrd0150" }," $$" :[{" #name" :" text" ," _" :" modified Rankin Scale PD" },{" #name" :" keyword" ," $" :{" id" :" kwrd0160" }," $$" :[{" #name" :" text" ," _" :" Parkinson disease PwS" },{" #name" :" keyword" ," $" :{" id" :" kwrd0170" }," $$" :[{" #name" :" text" ," _" :" people with stroke partial eta squared QoL" },{" #name" :" keyword" ," $" :{" id" :" kwrd0190" }," $$" :[{" #name" :" text" ," _" :" quality of life rBP" },{" #name" :" keyword" ," $" :{" id" :" kwrd0200" }," $$" :[{" #name" :" text" ," _" :" resting blood pressure rHR" },{" #name" :" keyword" ," $" :{" id" :" kwrd0210" }," $$" :[{" #name" :" text" ," _" :" resting heart rate RPE" },{" #name" :" keyword" ," $" :{" id" :" kwrd0220" }," $$" :[{" #name" :" text" ," _" :" rate of perceived exertion rSBP" },{" #name" :" keyword" ," $" :{" id" :" kwrd0230" }," $$" :[{" #name" :" text" ," _" :" resting systolic blood pressure |
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