基底节区生殖细胞瘤的影像学诊断

目的分析基底节区生殖细胞瘤的影像学表现,以提高诊断正确率。方法回顾性分析8例病理证实的基底节区生殖细胞瘤的临床、影像学及病理学资料。结果8例患者均为男性,年龄5～13岁,平均10.5岁。8例均有单侧肢体肌力改变,其中1例伴有颅压增高临床表现,该例CT及MRI扫描示肿瘤占位效应较明显,呈脑积水改变。CT及MRI扫描示4例有不同程度囊变坏死,2例可见不同程度的瘤周水肿,2例同侧大脑皮层有萎缩现象,2例病灶内见点状钙化灶;增强扫描示肿瘤强化较显著。病理学结果示肿瘤标本为灰红色,血供较丰富,4例见囊变坏死。结论基底节区生殖细胞瘤影像学表现具有一定的特征性,结合临床表现可进一步提高诊断正确率。

Imaging Diagnosis of Germinoma in Basal Ganglia Area

Objective To improve the diagnosis of germinomas in basal ganglia area by analysing the imaging manifestations.Methods Clinic,pathologic and medical imaging data of 8 cases of germinomas in basal ganglia area confirmed pathologically were analyzed retrospectively.Results 8 cases were all men,the age ranged from 5~13 years old with mean age of 10.5 years.All cases had change of muscle strength on one side of extremity,and one case accompanied by intracranial hypertension,this case was showed the effect of space occupying of the tumor obviously and hydrocephalus on CT and MRI.The findings of CT and MRI showed cystic degeneration in 4 cases,slight edema around the tumor in 2 cases,cortex atrophy of the same side of tumor in 2 cases and calcification in the tumor in 2 cases.All cases were enhanced greatly.The pathologic specimen with rich supply of blood was gray-red,and cystic degeneration was seen in 4 cases.Conclusion CT and MRI features of germinomas in basal ganglia area are quite characteristic,the improvement of diagnosis can be achieved in combination with clinical manifestation.