首页 | 本学科首页   官方微博 | 高级检索  
     

甲胎蛋白阴性肝癌的临床特点分析
引用本文:胡迎宾,李定国,陆汉明,吴建新. 甲胎蛋白阴性肝癌的临床特点分析[J]. 实用医学杂志, 2006, 22(5): 550-551
作者姓名:胡迎宾  李定国  陆汉明  吴建新
作者单位:200092,上海交通大学医学院附属新华医院消化内科
摘    要:目的:分析甲胎蛋白(alphafetoprotein,AFP)阴性肝癌的临床特点。方法:对11年间(1994-2004年)76例AFP阴性肝癌患者和2年间(2002-2003年)102例AFP阳性肝癌患者在性别、临床表现、合并疾病[乙型肝炎和(或)肝硬化]、Child-Pugh分级和γ-谷氨酰转移酶(γ-glutamyltransferase,γGT)方面进行对比分析。结果:AFP阴性肝癌患者消瘦乏力、腹痛、腹部肿块的症状少于AFP阳性肝癌患者(分别为55.3%vs82.4%、56.6%vs75.5%、13.2%vs45.1%,均P<0.05),合并乙型肝炎较AFP阳性肝癌少(68.4%vs93.1%,P<0.05),Child-Pugh分级中A级显著多于AFP阳性肝癌(56.6%vs32.4%,P<0.05),而C级显著少于AFP阳性肝癌(2.6%vs16.7%,P<0.05);AFP阴性肝癌患者中γGT异常者的比例少于AFP阳性肝癌(64.5%vs84.3%,P<0.05)。两组患者在黄疸、腹水、肝硬化和Child-Pugh分级中B级方面差异无显著性。结论:AFP阴性肝癌患者临床表现较轻且缺乏特异性,诊断...

关 键 词:肝肿瘤   甲胎蛋白类    
收稿时间:2005-09-08
修稿时间:2005-09-082005-10-20

Clinical characteristics of primary hepatic carcinoma(PHC) with the negative alpha-fetoprotein(AFP)
HU Ying-bin,LI Ding-guo,LU Han-ming,WU Jian-xin. Clinical characteristics of primary hepatic carcinoma(PHC) with the negative alpha-fetoprotein(AFP)[J]. The Journal of Practical Medicine, 2006, 22(5): 550-551
Authors:HU Ying-bin  LI Ding-guo  LU Han-ming  WU Jian-xin
Affiliation:Department of Digestive Diseases, Affiliated Xinhua Hospital, Medical School of Shanghai Jiao Tong University, Shanghai 200092, China
Abstract:Objective To study the clinical characteristics of primary hepatic carcinoma(PHC) with the negative alpha-fetoprotein(AFP). Methods Seventy-six patients with AFP-negative PHC were compared with 102 cases with AFP-positive PHC in sex, clinical situation, basic diseases(hepatitis B, liver cirrhosis),Child-Pugh grading and γ-glutamyl transferase(γGT). Results The presences of emaciation/weakness,abdominal pain and abdominal mass in AFP-negative PHC patients were less than those in AFP-positive PHC(55.3%vs 82.4...
Keywords:Liver neoplasms Alpha-fetoproteins
本文献已被 CNKI 维普 万方数据 等数据库收录!
点击此处可从《实用医学杂志》浏览原始摘要信息
点击此处可从《实用医学杂志》下载全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号