超声引导下肝脏穿刺瘤体内注射无水酒精治疗肝癌

目的:探讨超声引导下经皮肝内肿瘤穿刺注射无水酒精(PEI)治疗肝癌的疗效。方法:应用彩色多普勒超声引导经皮肝内肿瘤穿刺注射无水酒精治疗50例肝癌,每周1-2次,4-6次为1疗程,并对肿瘤大小变化进行检测。结果:治疗后3月彩超检查,其中3例肿块完全消失,23例肿块均有不同程度的缩小,另24例肿块无变化或增大。治疗后肿块中央回声增强,周边呈低回声,境界清晰,肿瘤内血流消失或减少。病人治疗后全身情况好转,症状减轻或消失,饮食明显增加,生活质量提高,甲胎蛋白(AFP)8例转阴,16例下降50%以上,无严重并发症发生。结论:超声引导酒精介入治疗对肝癌的治疗有较好的疗效,安全实用。

Percutaneous Ethanol Injection Under Color Doppler Flow Imaging Guidance for the Treatment of Hepatoma

Objective: To evaluate the feasibility of percutaneous ethanol injection(PEI) under color Doppler flow imaging(CDFI) in the treatment of hepatoma.Methods: Under the ultrasonic guidance,patients with hepatoma underwent PEI therapy,and ethanol was injected slowly into the center of tumors.With once or twice in a week,four to six successive injections were finished during a full period of treatment.Results: Three months after the treatment,the mean diameter of 23 lesions(nodules) were decreased and the blood flow in nodules disappeared.Tumor nodules disappeared in three cases after three months' follow-up.All patients showed relief or disappearance of the symptoms,significant increasing in appetites and the serum AFP was decreased in 24 patients.No serious complication was observed.Conclusion: PEI under the guidance of CDFI is an effective and safe treatment for hepatoma.