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活血祛湿方对肝内胆汁淤积型大鼠血清学指标的影响
引用本文:崔晶,卢秉久,李莹. 活血祛湿方对肝内胆汁淤积型大鼠血清学指标的影响[J]. 实用中医内科杂志, 2011, 25(11): 37-38. DOI: 10.3969/j.issn.1671-7813.2011.11.17
作者姓名:崔晶  卢秉久  李莹
作者单位:1. 辽宁中医药大学2009级,辽宁沈阳,110034
2. 辽宁中医药大学附属医院,辽宁沈阳,110034
摘    要:[目的]探讨活血祛湿方对ANIT诱导的肝内胆汁淤积型大鼠的疗效。[方法]将40只SD大鼠随机分为正常对照组、模型组、西药组和中药治疗组,每组各10只。模型组和正常对照组给予0.9%氯化钠注射液,西药组予以思美泰,中药组予以活血祛湿方,各组均日1次灌胃给药,给药时间从造模当天开始,7d后处死全部大鼠,观察各组的生化指标及LP-X。[结果]与模型组相比,中药治疗组TBIL、DBIL、TBA、ALT和ALP水平明显下降(P<0.05),LP-X含量明显减少(P<0.05)。[结论]活血祛湿方通过降低大鼠血清生化指标以及LP-X,减轻肝损伤,有效的治疗大鼠肝内胆汁淤积。

关 键 词:肝内胆汁淤积  活血祛湿方  TBIL  DBIL  ALP  LP-X

Influence of Huoxue Qushi Mthod on Serological Index of Cholestatic Hepatitis Rats
CUI Jing,LU Bing-jiu,LI Ying. Influence of Huoxue Qushi Mthod on Serological Index of Cholestatic Hepatitis Rats[J]. , 2011, 25(11): 37-38. DOI: 10.3969/j.issn.1671-7813.2011.11.17
Authors:CUI Jing  LU Bing-jiu  LI Ying
Affiliation:CUI Jing1,LU Bing-jiu2,LI Ying2(1.Liaoning University of Traditional Chinese Medicine,Shenyang 110032,Liaoning,China,2.Affiliated Hospital of Liaoning University of TCM,China)
Abstract:[Objective]To study the therapeutic effect of huoxue qushi method on cholestatic hepatitis rats by ANIT.[Methods]Forty rats were randomly divided into normalcontrol group.modle group,western medicine group and Chinese medicine treatment group,with ten rats in each group.Modle group and normal control group were treated 0.9% sodium chloride,western medicine group by S-adenosy methionine,Chinese medicine group by huoxue qushi method,filling the stomach once a day in each group,The treatment was given after mo...
Keywords:cholestatic hepatitis  huoxue qushi method  total bilirubin  direct bilirubin  alkaline phosphatase  lipoprotein-X  
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