Abstract: | Cephalosporins have a wide spectrum of antibacterial activity and low toxicity. They are widely used in animals. When the cephalosporins are discharged into the soil and sewage through the discharge of sewage from industrial production or by the discharge of feces after animal administration, the abundance of environmental microbial resistance genes (ARGs) and bacteria resistance in the environment will be increased. Thus, it will reduce the success of antibiotic treatment of bacterial infections. In this article, the adsorption, migration, degradation and other behaviors of cephalosporin antibiotics in the environment (soil, manure, and water), current residues and effects on environmental micro-ecology are reviewed, to attracted people’s attention to the residual harm of cephalosporin antibiotics in the |