Abnormality in saccadic eye movement in dementia. |
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| Authors: | H J Schewe R Uebelhack K Vohs |
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| Affiliation: | 1. Brain and Cognition, KU Leuven, Belgium;2. Leuven Autism Research (LAuRes), KU Leuven, Belgium;3. Parenting and Special Education Research Unit, KU Leuven, Belgium;4. Department of Child Psychiatry, UPC-KU Leuven, Belgium;1. Department of Neurology, Army Medical Center of PLA, Chongqing, People’s Republic of China;2. Postgraduate School, Bengbu Medical College, Bengbu, People’s Republic of China;3. Department of Molecular Biology, Army Medical Center of PLA, Chongqing, People’s Republic of China;4. Department of Neurology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, People’s Republic of China;5. Department of Neurology, No. 958 Hospital of PLA, Chongqing, People’s Republic of China;1. Department of Psychology, University of Amsterdam, Nieuwe Achtergracht 129-B, 1018 WT Amsterdam, The Netherlands;2. Department of Psychology, University of California, 1285 Franz Hall, Box 951563, Los Angeles, USA;3. Department of Education and Child Studies, Leiden University, Pieter de la Court gebouw, Wassenaarseweg 52, 2333 AK Leiden, The Netherlands;4. Research Priority Area Yield, University of Amsterdam, The Netherlands;5. Amsterdam Brain and Cognition, University of Amsterdam, The Netherlands;1. Department of Physiology, Konyang University, College of Medicine, Daejeon, South Korea;2. Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, IL, USA;3. Department of Anesthesiology, Yeosu Chonnam Hospital, Yeosu, South Korea;4. Department of Pediatric Surgery, Dankook University, College of Medicine, Cheonan, South Korea;5. Department of Ophthalmology, Konyang University Hospital, Daejeon, South Korea;6. Myunggok Medical Research Institute, Konyang University College of Medicine, Daejeon, South Korea;7. Department of Neuroscience, Johns Hopkins University, School of Medicine, Baltimore, MD, USA;1. Institute of Textile Science and Technology, Academic Assembly, Shinshu University, Ueda 386-8567, Japan;2. Hokkaido University, Sapporo 060-0808, Japan;3. School of Life Studies, Sugiyama Jogakuen University, Nagoya 464-8662, Japan;4. Hazard Evaluation and Epidemiology Research Group, National Institute of Occupational Safety and Health, Kiyose 204-0024, Japan;5. National Institute of Technology, Kushiro College, Kushiro 084-0916, Japan |
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| Abstract: | In a small (n = 15) clinically heterogeneous group of patients with dementia of the Alzheimer-type or vascular dementia, abnormally high frequency of saccadic intrusions during fixation was significantly correlated to the Mini-Mental-State-Examination (MMSE) scores. In addition, the latency of saccades and hypometric saccades also correlated significantly to MMSE-scores. The results point to the possible use of saccadic eye movement as a physiological marker of cognitive performance. |
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