怀化地区汉族献血员ABO、Rh血型系统及其基因频率分布调查

目的了解怀化地区汉族献血员ABO血型分布、基因频率分布情况。方法用凝集法对2476例汉族献血员进行ABO血型检测，计算ABO血型基因频率。结果怀化地区汉族献血员ABO血型及其基因频率分布情况：A型：32．35％（801／2476）；B型：23．14％（573／2476）；O型：37．00％（916／2476）；AB型：7．51％（186／2476）；p（A）为0．2244；q（B）为0．1676；r（0）为0．6079，男、女性之间ABO及Rh血型分布无显著性差异（P〉0．05）。结论怀化地区汉族献血员ABO血型及其基因频率分布与北方地区有差异，符合南方地区O基因频率较高的特征。

Investigation on ABO, Rh Blood Type Distribution and the Gene Frequencies of Han Ethnic Groups in Huaihua

Objective To investigate the information of ABO,Rh blood type distribution and the gene frequencies in Huaihua city. Methods 2476 Han ethnic blood donors were detected for ABO and Rh blood type by Agglutination method. Results The ranks of ABO blood group freqencies and A, B,O gene frequencies of Han ethnic groups in Huaihua were 32.35%, 23.14%, 37.00%, 7.51%,and p （A） 0.2244,q （B） 0.1676,r （O） 0.6079 respectively. There was no difference of ABO and Rh blood group distribution between male and female in a same ethnic group of Han ethnic groups in Huaihua （P〉0.05）. Conclusion There are differences about the distribution of ABO blood groups among different ethnic groups. A higher O gene frequency exists in Han ethnic groups in Huaihua city, and shows a structural feature similar to other populations living in southern China.