| 牛心包生物瓣远期损坏的原因分析 |
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| 引用本文： | 宋来凤,朱晓东,司文学. 牛心包生物瓣远期损坏的原因分析[J]. 中华胸心血管外科杂志, 1998, 14(6): 340-341 |
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| 作者姓名： | 宋来凤 朱晓东 司文学 |
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| 作者单位： | 100037,中国医学科学院,中国协和医科大学心血管病研究所,阜外心血管病医院 |
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| 摘 要： | 对１１４例，１１９个植入人体内１年以上损坏的瓣膜作了损坏原因的病理学分析。基本病损：９０．７６％为破损、３４．４５％钙化、５．０４％过度纤维覆盖。结果表明，胶原纤维变性是导致瓣叶破损和钙化的基础。瓣叶的应力集中处可加速胶原纤维变性。早期损坏以破损为主，而后期常是破损和钙化等多种病损因素的复合结果
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| 关 键 词： | 牛心包生物瓣 瓣膜替换 病理学 |
An Analysis of Causes of Deterioration of Bio-valve Grafts |
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| Song Laifeng,Zhu Xiaodong,Si Wenxue. An Analysis of Causes of Deterioration of Bio-valve Grafts[J]. Chinese Journal of Thoracic and Cardiovascular Surgery, 1998, 14(6): 340-341 |
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| Authors: | Song Laifeng Zhu Xiaodong Si Wenxue |
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| Abstract: | Aim:To analyze the causes of deterioration of biological prostheses of heart valves.Clinical material and method:119 damaged bioprosthesis valve were obtained from 114 patients who have underwent previous valve replacement.The pathological changes of the damaged valve prostheses were examined by light and electron nicroscopy.Results:The cause of damage of the prostheses are related to the degeneration of the leaflete and mechanical stress during heart contraction.The basic damages were showed as decomposition(90.76%),calcification(34.45%)and overgrowth of fibrous tissue(5.04%).Conclusion:The calcification of valve may be related to the degeneration of collagen. |
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| Keywords: | Bio valve grafts Valve replacement Pathology |
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