| 糖尿病患者过氧化低密度脂蛋白的测定及其临床意义 |
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| 引用本文： | 田浩明,梁荩忠.糖尿病患者过氧化低密度脂蛋白的测定及其临床意义[J].中华内分泌代谢杂志,1992,8(2):69-71. |
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| 作者姓名： | 田浩明 梁荩忠 |
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| 作者单位： | 华西医科大学附属第一医院内分泌科，华西医科大学附属第一医院内分泌科 成都，610041，成都，610041 |
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| 摘 要： | 分别应用磷钨酸氯化镁分步沉淀法与超速离心法分离并测定了15例正常人的LDL-C、过氧化LDL(OX-LDL)、HDL-C水平,对两种方法的测得值进行了比较,发现两种方法之间的测定值相近,相关性良好。然后用磷钨酸氯化镁分步沉淀法测定了71例糖尿病患者和35例正常人LDL-C、OX-LDL、HDL-C水平,发现糖尿病患者OX-LDL高于正常人,而伴有血管病变者OX-LDL升高更为明显。
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| 关 键 词： | 糖尿病 过氧化低密度脂蛋白 低密度脂蛋白胆固醇 高密度脂蛋白胆固醇 |
MEASUREMENT OF OXIPATIVE LDL AND ITS CLINICAL SIGNIFICANCE IN DIABETICS |
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| Tian Hao-ming,Liang Jin-zhong
Dept,of Endocrinology,The First Affiliated Hospital,West China University of Medical Sciences,Chengtu.MEASUREMENT OF OXIPATIVE LDL AND ITS CLINICAL SIGNIFICANCE IN DIABETICS[J].Chinese Journal of Endocrinology and Metabolism,1992,8(2):69-71. |
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| Authors: | Tian Hao-ming Liang Jin-zhong
Dept of Endocrinology The First Affiliated Hospital West China University of Medical Sciences Chengtu |
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| Institution: | Tian Hao-ming,Liang Jin-zhong
Dept,of Endocrinology,The First Affiliated Hospital,West China University of Medical Sciences,Chengtu 610041 |
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| Abstract: | Levels of LDL-C, oxidative LDL, HDL-C were determined following step precipitation with phosphotungstic acid/ MgCl2, and being compared with those following separation by uliracentrifugation. The results revealed that the values from the two methods are similar and correlated well. Oxidative LDL, LDL-C and HDL-C were measured by step precipitation with phosphotungstic acid/MgCl2 in 71 diabetic patients and 35 normal controls. Level of oxidative LDL in diabetic patients was higher than that in controls, and much higher in diabetics with vascular complications. |
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| Keywords: | Diabetes mellitus Oxidative LDL LDL HDL |
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