乳腺癌前哨淋巴结探查的研究进展

乳腺癌前哨淋巴结(sentinel lymph node, SLN)是乳腺癌淋巴转移通道中最先经历的第一级淋巴结。通过乳腺癌SLN预测乳腺癌区域淋巴结转移状况,为乳腺癌的准确分期和外科手术提供了重要的依据。根据示踪剂的不同,有两种方法可以探查乳腺癌SLN,其中使用放射性核素标记物作为示踪剂探查乳腺癌SLN是目前较具优势的方法,且不同于传统的淋巴显像;乳腺癌SLN探查的成功率受到诸多因素的影响,其探查技术亦需进一步的研究来提高。

Sentinel lymph node detection in breast cancer

The concept of sentinel lymph node(SLN)holds that the lymphatic effluent o f a tumor drains initially to one or two lymph nodes before other nodes receive the tumoral drainage.It is a great advance in breast cancer surgery to one or two lymph nodes before other nodes receive the tumoral drainage.It is a great advance in breast cancer surgery to predict regional nodal metastases by sentine l lymph node detection in breast cancer,which can give the more refinedstaging of breast cancer.According to the different tracers,there a re two ways to detect SLN.Using a radiopharmaceutical to identify SLN in breas t cancer is superior,and differs from traditional lymphoscintigraphy.Some fac tors could affect SLN detection in breast cancer,and many efforts should be tak en to improve SLN detection techniques.