急性脑梗死患者高压氧治疗前后检测血清NSE的临床价值

目的：探讨急性脑梗死患者高压氧治疗前后血清神经元特异性烯醇化酶（NSE）的动态变化及临床价值。方法：将急性脑梗死患者88例随机分为高压氧治疗组（44例）和常规治疗组（44例），分别测定入院后第1、7、14天的血清NSE水平，并与对照组结果相互比较。结果：急性脑梗死患者血清NES水平明显高于对照组（P〈0．01），高压氧治疗组第7、14天血清NSE水平与常规治疗组比较的显著性差异变化（P〈0．01）。结论：NSE可以作为反映脑梗死患者脑细胞损伤程度的灵敏指标，早期高压氧治疗有助于减轻脑梗死病情。

On Clinical Value of Serum NSE＇s Test Before and After Treatment of ACI Patients＇ High Pressure Oxygen

Objective： To explore the dynamic changes and clinical value of serum NSE＇s test before and after treatment of ACI patients＇ high pressure oxygen. Methods： We firstly divide 88 cases of ACI patients into two groups randomly： 44 cases as high pressure oxygen treatment group; the other 44 cases as regular treatment group. Then we test the serum NSE level on day 1^st, day 7^th and day 14^th after hopitalization respectively and make a contrast with the controls. Results： The serum NSE level of ACI patients is remarkably higher than the controls; there is obviously different changes of the serum NSE level in the high pressure treatment group on day 72 and day 142 from the regular group. Conclusion： NSE can be used as an indicator of the damage extent of the brain cells of the ACI patients and the early treatment of high pressure oxygen is helpful to ease the illness situation.