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富硒灵芝抗衰老作用的实验研究
引用本文:陈海英,杨红兵,韩晓辉,石玉娥.富硒灵芝抗衰老作用的实验研究[J].四川中医,2006,24(9):7-8.
作者姓名:陈海英  杨红兵  韩晓辉  石玉娥
作者单位:1. 河北医科大学西校区基础课部,河北,石家庄,050091
2. 蔚县人民医院,河北,蔚县,057000
基金项目:河北省科技攻关项目(编号:99276219D)
摘    要:目的:观察富硒灵芝的抗衰老作用。方法:制备大鼠D-半乳糖急性衰老模型,在此模型上用跳台法观察富硒灵芝(0.2g/kg、0.4g/kg、0.8g/kg)对大鼠学习、记忆行为及衰老相关酶(肝组织MDA,肝、脑SOD活力,血清MDA含量及SOD活性,脑、肝组织MAO-B活性)的影响。结果:富硒灵芝能延长大鼠跳台潜伏期,减少错误次数,明显改善衰老模型大鼠的学习记忆能力;明显提高血清及肝、脑组织中的SOD活性,同时可降低血清及肝脑组织中MDA的含量及MAO-B活性。结论:富硒灵芝具有明显的抗衰老作用。

关 键 词:富硒灵芝  抗衰老
文章编号:1000-3649(2006)09-0007-02
收稿时间:05 17 2006 12:00AM
修稿时间:2006年5月17日

Experimental study on antisenility effect of Ganoderma Lucidum rich in selenium
CHEN Haiying,YANG Hongbing,HanXiaohui,Shi Yue.Experimental study on antisenility effect of Ganoderma Lucidum rich in selenium[J].Journal of Sichuan of Traditional Medicine,2006,24(9):7-8.
Authors:CHEN Haiying  YANG Hongbing  HanXiaohui  Shi Yue
Institution:Fundamentals Department of Hebei Medical University ,Shijiazhuang HeBei 050091, China
Abstract:Objective:To observe the antisenility effect of Ganoderma Lucidum rich in selenium.Methods:model rats of D-galactose acute senility were made and to be observed the effect of Ganoderma Lucidum rich in selenium on its' activity of learning and memorizing and enzyme related to senility(MDA in hepatic tissue,SOD activity in liver and brain,MDA contend and SOD activity in serum,MAO-B activity in brain and hepatic tissue).Results: Ganoderma Lucidum rich in selenium could prolong the incubation period of diving,reduce the mistake frequency,improve significantly the ability of learning and memorizing of model rats;could increase the SOD activity in serum,brain and hepatic tissue,and at the same time could decrease the MDA content and MAO-B activity in serum,brain and hepatic tissue.Conclusion: Ganoderma Lucidum rich in selenium has a significant effect on antisenility.
Keywords:Ganoderma Lucidum rich in selenium  antisenility
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