| 毛细管区带电泳法测定复方磺胺嘧啶片中两组份的含量 |
| |
| 引用本文： | 王桂芳,张守尧,王秉钧. 毛细管区带电泳法测定复方磺胺嘧啶片中两组份的含量[J]. 华西药学杂志, 2001, 16(2): 124-125 |
| |
| 作者姓名： | 王桂芳 张守尧 王秉钧 |
| |
| 作者单位： | 第一军医大学珠江医院, |
| |
| 摘 要： | 目的建立一种用毛细管区带电泳法测定复方磺胺嘧啶片中磺胺嘧啶和甲氧苄啶含量的方法。方法用25 mmol*L-1硼砂缓冲液来分离，以氯霉素为内标，214 nm为测定波长。结果样品中二组份完全分离且呈良好线性关系，其模拟样品回收率分别为100.39%和100.77%，RSD分别为1.03%和0.81%(n=5)。结论方法简便、准确。
|
| 关 键 词： | 毛细管区带电泳法 复方磺胺嘧啶片 磺胺嘧啶 甲氧苄啶 含量测定 |
| 文章编号： | 1006-0103(2001)02-0124-02 |
| 修稿时间： | 2000-05-01 |
DETERMINATION OF TWO ACTIVE COMPONENTS IN COMPOUND SULFADIAZINE TABLETS BY CAPILLARY ZONE ELECTROPHORESIS |
| |
| WANG Gui-fang,ZHANG Shou-yao,WANG Bing-jun. DETERMINATION OF TWO ACTIVE COMPONENTS IN COMPOUND SULFADIAZINE TABLETS BY CAPILLARY ZONE ELECTROPHORESIS[J]. West China Journal of Pharmaceutical Sciences, 2001, 16(2): 124-125 |
| |
| Authors: | WANG Gui-fang ZHANG Shou-yao WANG Bing-jun |
| |
| Abstract: | OBJECTIVE:To establish a capillary zone electrophoresis method for the determination of compound sulfadiazine tablets.METHODS: The buffer was borax (25 mmol*L-1), the internal standard was chloramphenicol and the detective wavelength was 214 nm.RESULTS:The two components, sulfadiazine and trimethoprim, werecompletely separated and determined.The average recoveries (n=5) were 100.39% and 100.77%，RSD were 1.03% and 0.81%, respectively.CONCLUSION:The method was simple and accurate, and it could be used for the quality control of compound sulfadiazine tablets. |
| |
| Keywords: | Capillary zone electrophoresis(CZE) Compound sulfadiazine tablets Sulfadiazine Trimethoprim |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
