| BPH相关性抗原表达的临床意义 |
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| 引用本文： | 罗向阳,王伟,高建光. BPH相关性抗原表达的临床意义[J]. 临床泌尿外科杂志, 2005, 20(3): 158-159 |
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| 作者姓名： | 罗向阳 王伟 高建光 |
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| 作者单位： | 许昌市中心医院泌尿外科,河南,许昌,461000;郑州大学第三附属医院泌尿外科;郑州大学第一附属医院泌尿外科 |
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| 摘 要： | 目的:探讨BPH相关性抗原(BPSA)在BPH、前列腺癌(PCa)诊断中的作用。方法:采用免疫组织化学ABC法,用BPSA单克隆抗体对62例BPH患者、37例PCa患者及30例其他肿瘤组织标本中的BPSA表达进行检测。结果:BPSA在100% BPH、88% PCa组织中呈不同程度的阳性表达,且在BPH组织中呈明显高表达。非前列腺肿瘤组织染色均呈阴性。组织BPSA表达与肿瘤病理分级无相关性(P>0. 05)。结论:BPSA具有良好的组织器官特异性,有助于早期PCa和BPH的鉴别诊断。
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| 关 键 词： | 良性前列腺增生 前列腺肿瘤 良性前列腺增生相关性抗原 |
| 文章编号： | 1001-1420(2005)03-0158-02 |
| 修稿时间： | 2004-09-06 |
Significance of benign prostatic hyperplasia associated PSA antigen in diagnosis of prostate diseases |
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| Luo Xiangyang,WANG Wei,GAO Jianguang. Significance of benign prostatic hyperplasia associated PSA antigen in diagnosis of prostate diseases[J]. Journal of Clinical Urology, 2005, 20(3): 158-159 |
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| Authors: | Luo Xiangyang WANG Wei GAO Jianguang |
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| Affiliation: | LUO Xiangyang1 WANG Wei2 GAO Jianguang3 |
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| Abstract: | Objective:To investigate the expression of benign prostatic hyperplasia associated PSA (BPSA) in differential diagnosis among benign prostate hyperplasia(BPH).Prostate cancer(PCa) and non-prostatic tumors.Methods:Different prostatic tissues and non-prostatic tumors (BPH 62, PCa 37, non-prostatic malignancies 30) were analysed for the expression of BPSA by using ABC immunohistochemical staining.Results:All prostatic tissues but 5 cases of PCa were stained positively while all of the non-prostatic tumors were stained negatively. Cell grades of PCa were not statistically correlated with the BPSA expression level.Conclusions:BPSA was prostatic organic specific and could improve the diagnosis specificity among BPH and PCa. |
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| Keywords: | Benign prostatic hyperplasia Prostatic neoplasms Benign prostatic hyperplasia assocated PSA |
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