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Comparison of the efficacy and safety of the adalimumab biosimilar TQ-Z2301 and adalimumab for the treatment of Chinese patients with active ankylosing spondylitis: a multi-center,randomized, double-blind,phase III clinical trial |
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| Authors: | Li Jia Xue Zhixin Wu Zhenbiao Bi Liqi Liu Huaxiang Wu Lijun Liu Shengyun Huang Xiangyang Wang Yong Zhang Yan Qi Wufang He Lan Dai Lie Sun Lingyun Li Xiaomei Shuai Zongwen Zhao Yi Wang Yanyan Xu Jian Zhang Hao Yu Hao Chen Xiaoxiang Bao Chunde |
| Institution: | 1.Department of Rheumatology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China ;2.Department of Rheumatology and Immunology, Tangdu Hospital of the Fourth Military Medical University (Air Force Medical University), Xi’an, China ;3.Department of Rheumatology and Immunology, China-Japan Union Hospital of Jilin University, Changchun, China ;4.Department of Rheumatology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China ;5.Department of Rheumatology and Immunology, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China ;6.Department of Rheumatology and Immunology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China ;7.Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China ;8.Department of Traditional Chinese Medicine, Southwest Hospital, Army Medical University, Chongqing, China ;9.Department of Rheumatology, the First Central Hospital, Tianjin, China ;10.Department of Rheumatology and Immunology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China ;11.Department of Rheumatology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China ;12.Department of Rheumatology and Immunology, Institute of Translational Medicine, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China ;13.Department of Rheumatology, Anhui Provincial Hospital, Hefei, China ;14.Department of Rheumatology and Immunology, The First Affiliated Hospital of Anhui Medical University, Hefei, China ;15.Department of Rheumatology and Allergy, Xuanwu Hospital Capital Medical University, Beijing, China ;16.Department of Rheumatology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China ;17.Department of Rheumatology and Immunology, First Affiliated Hospital of Kunming Medical University, Kunming, China ;18.Department of Nephrology, The Third Xiangya Hospital, Central South University, Changsha, China ;19.Department of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China ; |
| Abstract: | Clinical Rheumatology - To assess the clinical equivalence of TQ-Z2301, a biosimilar of adalimumab, to the reference adalimumab in the treatment of Chinese patients with active ankylosing... |
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