Canine Babesiosis in China Caused by Babesia gibsoni: A Molecular Approach |
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| Authors: | Da-wei YAO Jing-ya JIANG Ze-zhong YU Dong-qin YAO De-ji YANG Yan-bing ZhAO |
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| Institution: | 1.College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China;2.YuXi Agriculture Vocation-Technical College, Yuxi, Yunnan, China |
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| Abstract: | BackgroundTo provide a point of reference to study the epidemiology and clinical expression of canine babesiosis in China.MethodsA total of 30 dogs infected with canine babesiosis were evaluated by mean of clinical history, physical examination, hematological, restriction fragment length polymorphism of PCR products (PCR-RFLP) and sequencing analysis.ResultThe most prevalent clinical abnormalities were lethargy (100%), anorexia (100%), pale or icteric mucous membranes (80%), fever (70%) and dark urine (70%). Hematology parameters revealed that anemia and thrombocytopenia were the major abnormalities in blood of dogs infected with canine babesia. The results of PCR-RFLP and sequencing analysis indicated that B. gibsoni was the main species responsible for canine babesiosis cases at the time of the study in Nanjing, China.ConclusionsThe results provide valuable information for better understanding of the epidemiology of canine babesiosis in China. |
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| Keywords: | Canine babesiosis Babesia gibsoni PCR-RFLP Epidemiology Hematology |
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