Association between metabolic syndrome and tooth loss: A systematic review and meta-analysis |
| |
Affiliation: | 1. Department of Oral and Maxillofacial Surgery, Manchester University NHS Foundation Trust, Manchester Royal Infirmary, Manchester, M13 9WL;2. University of Birmingham, College of Medical and Dental Sciences, Birmingham, B15 2TT;3. Department of General Surgery, New Cross Hospital, Wolverhampton, WV10 0QP;4. Department of Oral and Maxillofacial Surgery, University Hospital Birmingham, B15 2TH;1. Department of Anesthesia and Critical Care, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA;3. Section of Abdominal Organ Transplantation, Department of Surgery, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA |
| |
Abstract: | BackgroundThe authors conducted a systematic review and meta-analysis to verify the existence and level of scientific evidence concerning the association between metabolic syndrome (MetS), as the main exposure, and tooth loss (TL), as the outcome.Types of Studies ReviewedThrough electronic databases and partially through gray literature, the authors identified observational studies in adults. The authors used no date or language restrictions. The authors evaluated the studies’ methodological quality by using the Newcastle-Ottawa Scale. The authors conducted a random-effects model meta-analysis. The authors assessed the quality of evidence by using the Grading of Recommendations Assessment, Development and Evaluation criteria.ResultsTwelve studies met the eligibility criteria, and 9 were retained for the meta-analysis. Most were cross-sectional studies with good methodological quality. Participants with MetS had fewer teeth (standardized mean difference, −2.77; 95% confidence interval, −4.56 to −0.98) and an increased likelihood of lacking functional dentition (odds ratio, 2.37; 95% confidence interval, 1.89 to 2.96) than did those without MetS. The overall quality of evidence was very low.Conclusions and Practical ImplicationsBetter-conducted longitudinal studies are necessary to establish a causal relationship between MetS and TL to inform the best strategies to prevent TL in populations with MetS. |
| |
Keywords: | Metabolic syndrome tooth loss systematic review meta-analysis epidemiology BMI" },{" #name" :" keyword" ," $" :{" id" :" kwrd0080" }," $$" :[{" #name" :" text" ," _" :" Body mass index BP" },{" #name" :" keyword" ," $" :{" id" :" kwrd0090" }," $$" :[{" #name" :" text" ," _" :" Blood pressure F" },{" #name" :" keyword" ," $" :{" id" :" kwrd0130" }," $$" :[{" #name" :" text" ," _" :" Female FGIc" },{" #name" :" keyword" ," $" :{" id" :" kwrd0140" }," $$" :[{" #name" :" text" ," _" :" Fasting glucose levels GRADE" },{" #name" :" keyword" ," $" :{" id" :" kwrd0140a" }," $$" :[{" #name" :" text" ," _" :" Grading of Recommendations Assessment, Development and Evaluation HDL" },{" #name" :" keyword" ," $" :{" id" :" kwrd0150" }," $$" :[{" #name" :" text" ," _" :" High-density lipoprotein IDF" },{" #name" :" keyword" ," $" :{" id" :" kwrd0160" }," $$" :[{" #name" :" text" ," _" :" International Diabetes Federation JIS" },{" #name" :" keyword" ," $" :{" id" :" kwrd0170" }," $$" :[{" #name" :" text" ," _" :" Joint Interim Statement M" },{" #name" :" keyword" ," $" :{" id" :" kwrd0190" }," $$" :[{" #name" :" text" ," _" :" Male MetS" },{" #name" :" keyword" ," $" :{" id" :" kwrd0210" }," $$" :[{" #name" :" text" ," _" :" Metabolic syndrome MetS(−)" },{" #name" :" keyword" ," $" :{" id" :" kwrd0220" }," $$" :[{" #name" :" text" ," _" :" Without MetS MetS(+)" },{" #name" :" keyword" ," $" :{" id" :" kwrd0230" }," $$" :[{" #name" :" text" ," _" :" With MetS NA" },{" #name" :" keyword" ," $" :{" id" :" kwrd0240" }," $$" :[{" #name" :" text" ," _" :" Not applicable NCEP ATP III" },{" #name" :" keyword" ," $" :{" id" :" kwrd0250" }," $$" :[{" #name" :" text" ," _" :" National Cholesterol Education Program Adult Treatment Panel III NOS" },{" #name" :" keyword" ," $" :{" id" :" kwrd0270" }," $$" :[{" #name" :" text" ," _" :" Newcastle-Ottawa Scale PD" },{" #name" :" keyword" ," $" :{" id" :" kwrd0280" }," $$" :[{" #name" :" text" ," _" :" Periodontal disease TG" },{" #name" :" keyword" ," $" :{" id" :" kwrd0300" }," $$" :[{" #name" :" text" ," _" :" Triglyceride TL" },{" #name" :" keyword" ," $" :{" id" :" kwrd0310" }," $$" :[{" #name" :" text" ," _" :" Tooth loss WC" },{" #name" :" keyword" ," $" :{" id" :" kwrd0340" }," $$" :[{" #name" :" text" ," _" :" Waist circumference |
本文献已被 ScienceDirect 等数据库收录! |
|