| 益肾活血胶囊抗病毒性心肌炎的实验研究 |
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| 引用本文： | 胡善宏,刘昌伟,张维东. 益肾活血胶囊抗病毒性心肌炎的实验研究[J]. 职业与健康, 2007, 23(20): 1816-1817 |
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| 作者姓名： | 胡善宏 刘昌伟 张维东 |
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| 作者单位： | 1. 山东省日照市疾病预防控制中心,276800
2. 山东省医学科学院基础研究所 |
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| 摘 要： | 目的探讨益肾活血胶囊对病毒性心肌炎小鼠的治疗作用。方法选用BALB/C小鼠60只,随机分为正常对照组、模型组、益肾活血胶囊组、阳性药物组,每组分别给药后,测定LDH和AST活力,并进行组织病理学检测,各区测定值采用t检验进行组间比较。结果益肾活血组小鼠LDH、AST水平较模型组明显降低(P<0.01);组织病理学检测发现,心脏组织病理改变程度较模型组明显减轻。结论益肾活血胶囊对于病毒性心肌炎模型小鼠有一定的治疗作用。
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| 关 键 词： | 益肾活血胶囊 小鼠 乳酸脱氢酶 天冬氨酸氨基转氨酶 病理组织学 |
| 文章编号： | 1004-1257（2007）20-1816-02 |
| 收稿时间： | 2006-09-13 |
| 修稿时间： | 2006-09-13 |
Experimental Study of the Effect of Yishenhuoxue Capsules in Treating Viral Myocarditis |
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| HU Shan-hong,LIU Chang-wei,ZHANG Wei-dong. Experimental Study of the Effect of Yishenhuoxue Capsules in Treating Viral Myocarditis[J]. Occupation and Health, 2007, 23(20): 1816-1817 |
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| Authors: | HU Shan-hong LIU Chang-wei ZHANG Wei-dong |
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| Affiliation: | Rizhao Center for Disease Prevention and Control, Shandong, 276800, China |
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| Abstract: | [Objective]To explore the curative effect of Yishenhuoxue capsules in treating viral myocarditis. [Methods] 60 BALB/C rats were divided into 4 groups, namely, the normal control group, model group, Yishenhuoxue capsule group and the electropositive drug group; LDL and AST activity of the groups were determined and histopathological detection was made.[ Results]The level of LDH and AST of the Yishenhuoxue capsule group decreased significantly than that of the model group (P<0.01); histopathological detection found that the level of histopathological changes of the Yishenhuoxue capsule group was obviously lower than that of the model group. [Conclusion] A Yishenhuoxue capsule is effective in treating viral myocarditis. |
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| Keywords: | Yishenhuoxue capsules Mouse LDH AST Histopathology |
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