参芪肝康片(胶囊)质量标准研究

目的：研究修订参芪肝康片（胶囊）的质量标准。方法：采用薄层色谱法对制剂中当归、黄芪及五味子进行定性测定;采用高效液相色谱法对绿原酸进行定量测定,采用C18柱,流动相为乙腈-0.4%磷酸溶液（8：92）,检测波长为327 nm。结果：薄层色谱斑点清晰,分离度好,阴性无干扰。含量测定中绿原酸在201 000 mg的范围内线性关系良好（r=0.999 9）,片剂和胶囊剂的加样回收率分别为95.2%、102.4%。结论：修订方法简便、准确,进一步完善了参芪肝康片（胶囊）的质量标准,可作为两者的质量控制标准。

Quality Standard for Shenqi Gankang Tablets (Capsules)

Objective：To improve the quality standard for Shenqi Gankang tablets and capsules.Method：TLC was used to identify Radix Angelicae Sinensis,Radix Astragali and Fructus Schisnndrae Chinensis,and chlorogenic acid was determined by HPLC with a C18 column,the mobile phase of acetonitrile-0.4%pliosphoric aeid（8：92） and the detection wavelength at 327 nm.Result：The herbs could be identified by TLC.For chlorogenic acid,the linear range was from 20 to 1 000 ng,and the average recovery for Shenqi Gankang tablets and capsules was 95.2%and 102.4%,respectively.Conclusion：The method is simple and accurate,and can be used to control the quality of Shenqi Gankang tablets and capsules.