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IgG4相关性疾病
引用本文:林玮,张文.IgG4相关性疾病[J].中华临床免疫和变态反应杂志,2010(4):307-311.
作者姓名:林玮  张文
作者单位:中国医学科学院北京协和医学院北京协和医院风湿免疫科,北京100032
摘    要:IgG4相关性疾病是一种与IgG4淋巴细胞密切相关的慢性、系统性疾病,该类疾病以血清IgG4水平升高以及IgG4阳性细胞浸润多种器官和组织为特征,常见受累器官包括泪腺、胰腺和腹膜后间隙等,累及的器官或组织由于慢性炎症及纤维化进程可导致弥漫性肿大。该类疾病对皮质激素治疗反应良好。

关 键 词:IgG4相关性疾病

IgG4-related Disease
LIN Wei,ZHANG Wen.IgG4-related Disease[J].Chinese Journal of Allergy and Clinical Immunology,2010(4):307-311.
Authors:LIN Wei  ZHANG Wen
Institution:#(Department of Rheumatology,Peking Union Medical College Hospital,Chinese Academy of Medical Science & Peking Union Medical College,Beijing 100032,China)
Abstract:IgG4-related disease is a kind of chronic and systemic disease which is characterized by increased serum level of IgG4 and abundant IgG4-bearing plasma cell infiltration in the involved organs.The most commonly involved organs or tissues include the salivary glands,pancreas,and retroperitoneal space and so on.Affected organs or tissues may show a diffuse swelling as a result of chronic inflammatory process,accompanied with progressive fibrosis.In this article,we will review relevant literatures of this disorder.
Keywords:IgG4-related disease
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