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表皮松解性角化过度鱼鳞病1例
引用本文:徐艳妮,李森,郑军,沈剑鸣. 表皮松解性角化过度鱼鳞病1例[J]. 中国皮肤性病学杂志, 2010, 24(4)
作者姓名:徐艳妮  李森  郑军  沈剑鸣
作者单位:1. 天津医科大学第二医院皮肤病科,天津,300211
2. 天津市中心妇产医院新生儿科,天津,30005
摘    要:患儿男,22天。出生时周身皮肤潮红、大疱,伴脱屑。组织病理示角化过度,中度棘层肥厚,颗粒层和棘层上部细胞内透明角质颗粒粗大、深染而不规则,明显的空泡形成,见网状变性、表皮内水疱和棘层松解细胞,棘层下部和基底细胞层无异常。诊断:表皮松解性角化过度鱼鳞病。

关 键 词:表皮松解  角化过度  鱼鳞病

A Case of Epidermolytic Hyperkeratosis Ichthyosis
XU Yan-ni,LI Sen,ZHENG Jun,SHEN Jian-ming. A Case of Epidermolytic Hyperkeratosis Ichthyosis[J]. The Chinese Journal of Dermatovenereology, 2010, 24(4)
Authors:XU Yan-ni  LI Sen  ZHENG Jun  SHEN Jian-ming
Affiliation:XU Yan-ni1,LI Sen1,ZHENG Jun2,SHEN Jian-ming1(1.Department of Dermatology,the Second Hospital of Tianjin Medical University,Tianjin 300211,China,2.Department of Neonatology,Tianjin Central Hospital of Obstetrics , Gynecology,Tianjin 300052,China)
Abstract:A 22-day-old male newborn presented generalized erythema,bulla and peeling on his whole body since birth.Skin biopsy showed orthokeratotic hyperkeratosis and moderate acanthosis.Gross,dense and irregularly shaped keratohyaline granules were observed in the granular and upper spinous layers,in which obvious vacuolization,reticular degeneration,intraepidermal blisters and acantholytic cells were found.No abnormalities were found in the lower spinous and basal layers.Diagnosis of epidermolytic hyperkeratosis i...
Keywords:Epidermolysis  Hyperkeratosis  Ichthyosis  
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