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国产五氟利多不良反应的临床分析
引用本文:方贻儒,王祖承.国产五氟利多不良反应的临床分析[J].中国药事,1992,6(2):118-121.
作者姓名:方贻儒  王祖承
作者单位:上海第二医科大学精神医学教研室 200030 (方贻儒),上海第二医科大学精神医学教研室 200030(王祖承)
摘    要:上海市精神卫生中心自1979~1990年间给150个病例使用了国产五氟利多药品,在有完整记录资料的126例中54例出现了各种不良反应.其中单独用药26例,有11例(42.3%)出现不良反应,多见的依次为震颤、静坐不能、运动不能、心动过速等.

关 键 词:五氟利多  精神分裂症  药物不良反应  震颤  静坐不能

A Clinical Analysis of the Adverse Drug Reactions Induced by Domestic Penflurido!
Fang Yiru and Wang Zucheng.A Clinical Analysis of the Adverse Drug Reactions Induced by Domestic Penflurido![J].Chinese Pharmaceutical Affairs,1992,6(2):118-121.
Authors:Fang Yiru and Wang Zucheng
Institution:Department of Psychological Medicine of the No.2 Shanghai Medical University
Abstract:A total of 150 patients treated with long-acting anticholinergic, penflu-ridol from 1979 to December 1990 by the Shanghai Center for Mental Health was investigated, and 126 cases ( 89 males and 37 females ) of them with complete medical records were reviewed. Fifty-four cases ( 42.9% ) were found to have adverse drug reactions. Among them 26 cases were only treated with penfluridol and adverse reactions, such as tremor, akathisia, akinesia, and tachycardia, occurred in n cases(42.3% ) out of them. The common management was a combined use of anticholinergics ( 61.1% ).
Keywords:Penfluridol  schizophrenia  adverse drug reaction  tremor  akathisia
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