中药熏蒸治疗绝经后骨质疏松症腰背痛临床研究

目的：观察中药熏蒸治疗绝经后骨质疏松症腰背痛的临床疗效。方法：选取120 例绝经后骨质疏松症腰背痛患者作为研究对象，以随机数字表法分为对照组及观察组各60 例。对照组给予常规治疗（钙剂、维生素D、注射鲑鱼降钙素），观察组在对照组基础上联合中药熏蒸治疗。比较2 组治疗前后疼痛视觉模拟评分法（VAS） 评分、腰椎功能评分（JOA）、生活质量综合评定问卷-74（GQOLI-74） 评分、腰椎骨密度，并比较2 组临床疗效及不良反应。结果：治疗后，2 组VAS 评分均降低（P＜0.05），且观察组低于对照组（P＜0.05）。观察组治疗总有效率96.67%，高于对照组83.33% （P＜0.05）。治疗后，2 组JOA 评分均升高（P＜0.05），且观察组高于对照组（P＜0.05）。随访3 个月，2 组GQOLI-74 评分均升高（P＜0.05），且观察组躯体功能、心理功能维度GQOLI-74 评分高于对照组（P＜0.05）。治疗后，2 组腰椎骨密度均升高（P＜0.05），且观察组高于对照组（P＜0.05）。2 组不良反应发生率比较，差异无统计学意义（P＞0.05）。结论：中药熏蒸可提升绝经后骨质疏松症腰背痛患者的临床疗效，且能进一步改善患者腰背疼痛症状，帮助患者恢复腰椎功能，增加骨密度，提高生活质量。

Clinical Study on Chinese Medicine Fumigation for Postmenopausal OsteoporosisComplicated with Low Back Pain

Abstract：Objective：To observe the clinical effect of Chinese medicine fumigation on postmenopausalosteoporosis complicated with low back pain. Methods： A total of 120 patients with postmenopausalosteoporosis complicated with low back pain were selected as the study subjects and divided into thecontrol group and the observation group according to the random number table method，with 60 cases ineach group. The control group was given routine treatment (Calciums，Vitamin D，and Salmon Calcitoninfor Injection)，and the observation group was additionally treated with Chinese medicine fumigation basedon the treatment of the control group. The scores of Visual Analogue Scale (VAS) of pain， JapaneseOrthopaedic Association (JOA) of lumbar vertebral function， and Generic Quality of Life Inventory- 74(GQOLI- 74)，and the bone mineral density of lumbar vertebra were compared before and after treatmentbetween the two groups； the clinical effects and incidence of adverse reactions were also comparedbetween the two groups. Results：After treatment，the VAS scores in the two groups were decreased (P＜0.05)，and the VAS score in the observation group was lower than that in the control group (P＜0.05). Thetotal effective rate was 96.67% in the observation group，higher than that of 83.33% in the control group(P＜0.05). After treatment， the JOA scores in the two groups were increased (P＜0.05)， and the JOAscore in the observation group was higher than that in the control group (P＜0.05). After follow- up of3 months，the GQOLI-74 scores in the two groups were increased (P＜0.05)，and the GQOLI-74 scoresof physical functioning and mental functioning in the observation group were higher than those in the controlgroup (P＜0.05). After treatment， the bone mineral density of lumbar vertebral in the two groups wasincreased (P＜0.05)，and the bone mineral density of lumbar vertebral in the observation group was higherthan that in the control group (P＜0.05). There was no significant difference being found in the comparisonof incidence of adverse reactions between the two groups (P＞0.05). Conclusion： Chinese medicinefumigation can enhance the clinical effect on postmenopausal osteoporosis complicated with low backpain， further improve the symptoms of low back pain， help recover the lumbar vertebral function，increase the bone mineral density and enhance the quality of life.