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重组牛碱性成纤维细胞生长因子凝胶联合CO2点阵激光治疗痤疮后面部凹陷性瘢痕的疗效
引用本文:袁波. 重组牛碱性成纤维细胞生长因子凝胶联合CO2点阵激光治疗痤疮后面部凹陷性瘢痕的疗效[J]. 医学美学美容, 2024, 33(4): 105-108
作者姓名:袁波
作者单位:江南大学附属无锡五院/无锡市第五人民医院皮肤科
摘    要:研究对痤疮后面部凹陷性瘢痕患者应用重组牛碱性成纤维细胞生长因子凝胶联合CO2点阵激光治疗的效果。方法 选取2019年3月-2022年3月江南大学附属无锡五院/无锡市第五人民医院收治的痤疮后面部凹陷性瘢痕患者80例作为研究对象,按照随机数字表法分为参照组和分析组,每组40例。参照组应用CO2点阵激光治疗,分析组应用重组牛碱性成纤维细胞生长因子凝胶联合CO2点阵激光治疗,比较两组临床疗效、临床指标(结痂时间、疼痛时间、红斑持续时间)、不良反应发生情况。结果 分析组治疗总有效率为95.00%,高于参照组的72.50%(P <0.05);分析组结痂时间、疼痛时间、红斑持续时间短于参照组(P <0.05);分析组不良反应发生率为2.50%,低于参照组的22.50%(P <0.05)。结论 重组牛碱性成纤维细胞生长因子凝胶联合CO2点阵激光治疗痤疮后面部凹陷性瘢痕的效果良好,可缩短患者的结痂时间、疼痛时间及红斑持续时间,且安全性较高。

关 键 词:重组牛碱性成纤维细胞生长因子;痤疮;面部凹陷性瘢痕;点阵激光;结痂时间

Effect of Recombinant Bovine Basic Fibroblast Growth Factor Gel Combined with CO2Fractional Laser in the Treatment of Facial Depressed Scar After Acne
YUAN Bo. Effect of Recombinant Bovine Basic Fibroblast Growth Factor Gel Combined with CO2Fractional Laser in the Treatment of Facial Depressed Scar After Acne[J]. Journal of Medical Aesthetics and Cosmetology, 2024, 33(4): 105-108
Authors:YUAN Bo
Affiliation:Department of Dermatology, Wuxi Fifth Hospital Affiliated to Jiangnan University/Wuxi Fifth People''s Hospital,
Abstract:To study the therapeutic effect of recombinant bovine basic fibroblast growth factor gel combined with CO2fractional laser on patients with facial depression scar after acne. Methods A total of 80 patients with facial depressed scar afteracne admitted to Wuxi Fifth Hospital Affiliated to Jiangnan University/Wuxi Fifth People''s Hospital from March 2019 to March2022 were selected as the research objects. According to the random number table method, they were divided into reference groupand analysis group, with 40 patients in each group. The reference group was treated with CO2 fractional laser, and the analysis groupwas treated with recombinant bovine basic fibroblast growth factor gel combined with CO2 fractional laser. The clinical effects,clinical indicators (scab formation time, pain time, erythema duration) and incidence of adverse reactions were compared betweenthe two groups. Results The total effective rate of treatment in the analysis group was 95.00%, which was higher than 72.50% inthe reference group (P <0.05). The scab time, pain time and erythema duration in the analysis group were shorter than those in thereference group (P <0.05). The incidence of adverse reactions in the analysis group was 2.50%, which was lower than 22.50% in thereference group (P <0.05). Conclusion Recombinant bovine basic fibroblast growth factor gel combined with CO2 fractional laseris effective in the treatment of facial depressed scars after acne, which can shorten the scab formation time, pain time and erythemaduration of patients, and has high safety.
Keywords:Recombinant bovine basic fibroblast growth factor   Acne   Depressed facial scar   Fractional laser   Scab time
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