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加味四逆散对肝硬化患者血清胃肠激素变化的临床观察
引用本文:苏全武,邱明义. 加味四逆散对肝硬化患者血清胃肠激素变化的临床观察[J]. 中国中西医结合消化杂志, 2008, 16(6): 375-377
作者姓名:苏全武  邱明义
作者单位:1. 随州市中心医院,感染科,湖北,随州,441300
2. 湖北中医学院,伤寒教研室,湖北,武汉,430065
摘    要:[目的]观察加味四逆散对肝硬化患者胃肠激素血浆浓度的影响,并探讨其临床意义。[方法]150例肝硬化并胃动力障碍患者随机分为2组,对照组采用基础治疗,给予能量合剂、还原型谷胱甘肽、甘草酸制剂等保肝药物外,并给予口服西沙比利片5mg/次,3次/d;治疗组在基础治疗上加用加味四逆散,疗程均为15d。用放射免疫法测定2组患者治疗前后血清胃动素(MOT)、促胃液素(GAS)、血管活性肠肽(VIP)和生长抑素(SS)的水平。[结果]2组患者治疗后血清MOT、VIP、GAS、SS水平较治疗前均有明显变化(P〈0.05,〈0.01),2组间比较差异有统计学意义(P〈0.05)。[结论]加味四逆散能明显改善肝硬化患者胃动力障碍症状,改善血清胃肠激素水平。

关 键 词:肝硬化  胃肠激素  加味四逆散

Therapeutic effect of Jiawei Sini decoction (JWSND) on gastric motility in patients with hepatic cirrhosis
SU Quan-wu,QIU Ming-yi. Therapeutic effect of Jiawei Sini decoction (JWSND) on gastric motility in patients with hepatic cirrhosis[J]. Chinese Journal of Integrated Traditional and Western Medicine on Digestion, 2008, 16(6): 375-377
Authors:SU Quan-wu  QIU Ming-yi
Affiliation:SU Quan-wu1,QIU Ming-yi2(1 Hospital of suizhou city,suizhou 441300,China,2HuBei Traditional Chinese Medicine college Tutor,Wuhan 430065,China)
Abstract:[Objective]To observe the effect of JWSND on the serum gastrointestinal hormone in patients with liver cirrhosis.[Methods]One hundred and fifty patients with obstacle of gastric motility were randomly divided into two groups.Seventy five patients in control group were treated by basic treatment,which used Energic mixture,Reduced Glutathione,Compound Glycyrrhizin.Seventy five patients in treatment group were treated by combination of JWSND and routine therapy.The course was 15 days in both groups,serum MOT,G...
Keywords:hepatic cirrhosis  gastrointestinal hormone  JWSND  
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