Styrene-7,8-oxide in blood of workers exposed to styrene |
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| Authors: | M Korn W Gfrörer J G Filser W Kessler |
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| Institution: | 1. Institut für Arbeits- und Sozialmedizin, Wilhelmstr. 27, 72074, Tübingen, Germany
2. GSF-Institut für Toxikologie, Neuherberg, 85758, Oberschlei?heim, Germany
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| Abstract: | A field study was carried out on 13 workers exposed to styrene vapors at time-weighted average concentrations between 10
and 73 ppm. The reactive intermediate styrene-7,8-oxide was determined in blood samples using a direct gas chromatographic
method. Styrene-7,8-oxide concentrations were in the range between 0.9 and 4.1 μg/l blood. Linear correlations were found
between styrene-7,8-oxide in blood and styrene in ambient air and blood. For an exposure concentration of 20 ppm styrene (German
MAK value) a steady-state level of about 1 μg styrene-7,8-oxide/l blood was calculated.
Received: 3 February 1994/Accepted: 7 April 1994 |
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| Keywords: | : Styrene – Styrene-7 8-oxide – Blood concentration – Man – Field study – Capillary gas chromatography |
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