47例老年恶性肿瘤患者肺部真菌感染的临床分析

目的探讨老年恶性肿瘤患者肺部真菌感染的发生率,并分析引起真菌感染的致病条件及危险因素等.方法采用回顾性调查研究的方法对2002年12月～2004年12月在我院住院的老年恶性肿瘤患者调查.结果在调查的113名患者中,有47名患者发生肺部真菌感染,感染率为41.59%.念珠菌是最常见的感染菌种,尤其是白色念珠菌（36株,65.45%）.在单因素分析中,住院时间、患者年龄、使用广谱抗生素种类数、合并严重细菌感染,具有COPD基础、气管插管为发生肺部真菌感染的危险因素.结论老年恶性肿瘤患者肺部真菌感染发生率较高,应采取有效措施,控制各类危险因素,切实降低其发病率.

Clinical analyse of pulmonary fungal infections in malignancy elderly patients

Objective To discuss the morbidity of pulmonary fungal infections in malignancy elderly patients.Methods A retrospective study on all the malignancy elderly patients of our hospital between December 2003 and December 2004 was conducted.Results One hundred and thirteen cases were investigated.Pulmonary fungal infection were found in 47 cases(41.59%).Candida spp was the majorpathogens,especially Candida albicans(36strains,65.45%).The days in hospital,the age,usage of broadspectrum antibiotic,critical bacterial infection,COPD,and trachealcannula were significant risk factors.Conclusion The morbidity of pulmonary fungal infection malignancy elderly patients was quite high.It is imperative to make efforts to reduce the morbidity pulmonary fungal infection in malignancy elderly patients.