降钙素原在儿童呼吸道细菌性感染诊断中的应用

目的研究血清降钙素原（PCT）在儿童呼吸道细菌性感染诊断中的实用价值。方法回顾性研究儿童呼吸道细菌性感染患者86例,根据儿童呼吸道感染的病原体诊断标准分为细菌性感染组（54例）和非细菌性感染组（32例）,检测并比较两组PCT和C反应蛋白（CRP）值,将两组数据进行统计学分析。结果细菌性感染组患者血清中PCT水平为（1.04±0.47）μg/L,高于非细菌性感染组的（0.20±0.08）μg/L,差异有统计学意义（P〈0.05）,CRP水平与非细菌性感染组比较差异无统计学意义（P〉0.05）。54例细菌性感染组患者血清中,PCT增高48例,CRP增高35例,差异有统计学意义（P〈0.05）,PCT和CRP诊断细菌性儿童呼吸道感染不存在一致性。结论 PCT对儿童呼吸道是否细菌感染具有明显的临床诊断价值。

Application of procalcitonin to diagnosis of children respiratory tract bacterial infection

Objective To evaluate the practical value of procatcitonin（PCT） in diagnosis of children respiratory tract bacterial infection. Methods A total of 86 children with respiratory tract infection were restrospectively analyzed. According to the diagnostic criteria of pathogens of infection, 54 cases were enrolled in bacterial infection group and 32 cases in non-bacterial infection group. The PCT level and the C-reactive protein（CRP） level of the two groups were determined and compared with each other. Results The PCT level was （1.04±0.47）μg/L in the bacterial in- fection group and higher than （0.20± 0.08）μg/L in the non-bacterial infection group with statistical difference between the two groups（P〈0.05）. The CRP level between the bacterial infection group and the non-bacterial infection group had no statistical difference（P〉0.05）. Among 54 cases of bacterial infection, serum PCT was increased in 48 cases and CRP was increased in 35 cases with statistical difference. Conclusion PCT has obvious value to diagnose respiratory tract bacterial infection in clinic.