| 肠促胰岛素在减肥手术治疗肥胖2型糖尿病患者中的作用 |
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| 引用本文： | 侯文芳,刘国强,洪天配. 肠促胰岛素在减肥手术治疗肥胖2型糖尿病患者中的作用[J]. 世界华人消化杂志, 2010, 18(4) |
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| 作者姓名： | 侯文芳 刘国强 洪天配 |
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| 作者单位： | 北京大学第三医院内分泌科,北京市,100191;北京大学第三医院内分泌科,北京市,100191;北京大学第三医院内分泌科,北京市,100191 |
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| 基金项目： | 国家自然科学基金资助项目;No.30700879国家973、863重大项目子课题基金资助项目;No.2006AA02A112北京市自然科学基金资助项目 |
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| 摘 要： | 肥胖和2型糖尿病的患病率呈逐年增高的趋势.减肥手术作为减轻体质量的有效方法,近年来逐渐得到广泛的应用.其主要分为限制型手术、吸收不良型手术及联合型手术.减肥手术在减轻体质量的同时也使肥胖患者的糖尿病得到了缓解,但其缓解糖尿病的机制目前尚不完全清楚.除了体质量减轻、摄食减少外,关于肠促胰岛素在减肥手术中的作用也受到了越来越多的重视.本文对减肥手术的术式、疗效、安全性及治疗糖尿病的可能机制进行讨论.
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| 关 键 词： | 减肥手术 2型糖尿病 肠促胰岛素 |
Remission of type 2 diabetes in obese patients after bariatric surgery:the role of incretins |
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| Wen-Fang Hou,Guo-Qiang Liu,Tian-Pei Hong. Remission of type 2 diabetes in obese patients after bariatric surgery:the role of incretins[J]. World Chinese Journal of Digestology, 2010, 18(4) |
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| Authors: | Wen-Fang Hou Guo-Qiang Liu Tian-Pei Hong |
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| Affiliation: | Wen-Fang Hou,Guo-Qiang Liu,Tian-Pei Hong,Depart- ment of Endocrinology,Peking University Third Hospital,Beijing 100191,China |
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| Abstract: | The prevalence of obesity and type 2 diabetes has increased over recent decades.Bariatric surgery has been widely used in clinical practice. There are three categories of bariatric surgery: restrictive surgery,malabsorptive surgery,and combined restrictive and malabsorptive surgery. Bariatric surgery causes not only weight loss but also a remarkable and durable remission of type 2 diabetes mellitus.However,the mechanism of diabetes resolution remains unclear.In addition to weight loss and food intake restri... |
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| Keywords: | Bariatric surgery Type 2 diabetes mel- litus Incretin |
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