生物羊膜移植在翼状胬肉手术中的临床应用

目的: 观察生物羊膜移植术治疗翼状胬肉的临床疗效及复发率,为翼状胬肉的诊疗提供参考。方法: 本研究在2010-04/2012-04期间对52例58眼翼状胬肉患者施行了显微镜下切除联合生物羊膜移植术,观察其角膜上皮修复时间和术后复发率,并与同期单纯接受显微镜下翼状胬肉切除术的46例53眼患者进行对照研究。结果: 研究组患者的复发率显著低于对照组。研究组患者在术后第3,5d即愈合的例数所占比例显著高于对照组,而在14d后愈合的例数所占比例显著低于对照组,另外对照两组患者的平均愈合天数发现研究组患者显著短于对照组。另外研究组患者的舒适度显著高于对照组。结论: 显微镜下翼状胬肉切除联合生物羊膜移植术术后角膜上皮修复时间更短,术后复发率更低,舒适度更高,值得推荐。

Clinical application of biological amnion transplantation in pterygium operation

AIM: To observe the clinical effect and recurrence rate of biological amnion transplantation in pterygium operation, and to provide the reference for pterygium diagnosis.

METHODS: Fifty-two patients(58 eyes)with pterygium were conducted microscope excision combined with biological amnion transplantation from April, 2010 to September, 2012. The repair time of corneal epithelium and postoperative recurrence rate were recorded. Forty-six patients(53 eyes)receiving excision of pterygium with microscope alone at the same term were selected to make a controlled study.

RESULTS: The recurrence rate of patients in research group was significantly lower than that in control group. The proportion of healing cases in research group on the 3^rd and 5^th days after operation were remarkably higher than that in control group, while that on the 14^th day conspicuously lower than that in control group. The mean healing days of patients in research group were markedly shorter than that in control group. In addition, the patient comfort of the research group was significantly higher than that in control group.

CONCLUSION: Excision of pterygium with microscope combined with biological amnion transplantation can effectively shorten the postoperative repair time of corneal epithelium, decrease the recurrence rate distinctly, and is more comfortable, so it deserves to be recommended.