弱视眼黄斑区视网膜厚度的光学相干断层扫描

目的: 通过检测远视性屈光不正性弱视患者弱视眼黄斑区视网膜厚度,探索弱视患者黄斑区视网膜发育状况。方法: 应用光学相干断层扫描系统(OCT)检测弱视组17例20眼及正常对照组14例20眼黄斑中心区及黄斑周围区视网膜厚度。用SPSS13.0统计软件分析两组视网膜平均厚度的差异。结果: 黄斑中心区厚度弱视组比正常对照组厚,差异具有统计学意义(P<0.05)。黄斑周围区内环弱视组鼻侧视网膜厚度与正常对照组鼻侧比较差异有显著性(P<0.05),弱视组颞侧及上、下方视网膜厚度分别与正常对照组比较差异均无显著性(P>0.05)。而黄斑周围外环各区视网膜厚度弱视组和正常对照组相比差异均无统计学意义(P>0.05)。结论: 远视性屈光不正性弱视眼黄斑中心区视网膜厚度增加,OCT技术为非侵入性、结果可靠、安全。能否用于客观评估弱视预后及检测弱视治疗效果有待进一步研究。

Optical coherence tomography examination of patients with hyperopic ametropic amblyopia

AIM: To investigate the changes of retina in amblyopic eye by measuring macular retinal thickness in hyperopicametropic amblyopic patients.

METHODS: Optical coherence tomography(OCT)was used to measure the macular retinal thickness value in 17 amblyopic patients(20 eyes)and 14 healthy controls(20 eyes). The result was processed as retinal thickness value and thickness map by computer. The data were analyzed by SPSS 13.0 software package.

RESULTS: The retinal thickness of central sector or region in amblyopic eyes were thicker than those in normal eyes(P<0.05), in the inner ring, the difference of nasal quadrant between amblyopic eyes and normal eyes was statistically significant(P<0.05), but there was no significant difference in other three quadrants of the inner ring and in any quadrant of the outer ring between amblyopic eyes and normal eyes(P>0.05).

CONCLUSION: The macular retina thickness of the central region is thicker in hyperopic ametropic amblyopic patient. OCT is a noninvasive, noncontact technique that visualizes the retinal structure in vivo, this technique may be used to find the potential initial neural site of the visual deficit in this condition.