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Collagen induced arthritis (CIA) in mice features regulatory transcriptional network connecting major histocompatibility complex (MHC H2) with autoantigen genes in the thymus |
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| Authors: | Donate Paula B Fornari Thaís A Junta Cristina M Magalhães Danielle A Macedo Cláudia Cunha Thiago M Nguyen Catherine Cunha Fernando Q Passos Geraldo A |
| Affiliation: | a Molecular Immunogenetics Group, Department of Genetics, Faculty of Medicine of Ribeirão Preto, University of São Paulo (USP), 14040-900 Ribeirão Preto, SP, Brazil b Department of Pharmacology, Faculty of Medicine of Ribeirão Preto, USP, 14040-900 Ribeirão Preto, SP, Brazil c National Institute of Health and Medical Research (INSERM U928) 13100 Marseille, France d Disciplines of Genetics and Molecular Biology, Department of Morphology, Faculty of Dentistry of Ribeirão Preto, USP, 14040-904 Ribeirão Preto, SP, Brazil |
| Abstract: | |
| Keywords: | CII, type II collagen CIA, collagen induced arthritis CFA, complete Freud's adjuvant HLA, human leukocyte antigen MHC, major histocompatibility complex PBS, phosphate-buffered saline PGE, promiscuous gene expression PTA, peripheral tissue autoantigens TEC, thymic epithelial cell cTEC, cortical thymic epithelial cell mTEC, medullary thymic epithelial cell RA, rheumatoid arthritis SAM, significance analysis of microarrays |
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