^aSchool of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan, ROC

^bDepartment of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan, ROC

^cInstitute of Immunology, Chung Shan Medical University Hospital, Taichung, Taiwan, ROC

^dInstitute of Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC

^eHung Kuang University, Taichung, Taiwan, ROC