针药结合治疗慢性萎缩性胃炎肠化生的疗效观察

目的:寻求治疗慢性萎缩性胃炎胃黏膜肠化生的有效方法.方法:将51例经胃镜及病理检查确诊为伴有肠化生的慢性萎缩性胃炎患者随机分为针药结合组(26例)和单纯中药组(25例).单纯中药组以衍化四君子汤加减;针药结合组以中脘、足三里、内关、公孙为主穴针刺并加中药治疗,中药同单纯中药组.经3个月治疗后,复查胃镜和病理,以临床症状、胃镜观察、黏膜组织病理活检等为指标,对两组疗效进行比较.结果:在改善临床症状方面,二组疗效差异无显著性意义(P>0.05);胃镜检查方面,针药结合组的总有效率88.46%优于单纯中药组的64.00%(P<0.05);对肠化生的病理改善方面,针药结合组的总有效率84.62%亦优于单纯中药组的64.00%(P<0.05).结论:针药结合可作为治疗慢性萎缩性胃炎胃黏膜肠上皮化生的较佳方法.

Observation on therapeutic effect of acupuncture combined with drug for treatment of intestinal me-taplasia of chronic atrophic gastritis

Objective To search for an effective method for treatment of intestinal metaplasia of gastric mucosa in the patient of chronic atrophic gastritis. Methods Fifty-one cases of chronic atrophic gastritis with intestinal metaplasia were randomly divided into a treatment group (n = 26) and a control group (n = 25). The treatment group were treated with acupuncture at main acupoints: Zhongwan (CV 12) , Zusanli (ST 36), Neiguan (PC 6), Gongsun (SP 4) ,and oral administration of modified Sijunzi Decoction, and the control group with the modified Sijunzi Decoction. After treatment for 3 months, clinical symptoms, results of gastroscopy and pathological changes of gastric mucosa were compared between the two groups. Results There was no significant difference in improvement of the clinical symptoms between the two groups (P>0. 05),the total effective rate of 88.46% for gastroscopy in the treatment group was better than 64. 00% in the control group (P<0. 05); and the total effective rate of 84. 62% for pathological improvement of intestinal metaplasia in the treatment group was superior to 64. 00% in the control group (P<0. 05). Conclusion Acupuncture combined with Chinese drug is a better therapy for intestinal metaplasia of gastric mucosa in the patient of chronic atrophic gastritis.