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Diarrhoea-related morbidity and rotavirus infection in France
Authors:JC Desennclos,I Rebiè  re,L letrillard,A Flahault,B Hubert
Affiliation:Réseau National de SantiéPublique CHU de Tours, Tours, Frannce;Saint-Maurice;INSERM CHU de Tours, Tours, Frannce;Paris and Service d'Information Médicale CHU de Tours, Tours, Frannce
Abstract:To assess the importance of diarrhoea in France and, speecifically, rotavirus-related diarrhoea among children, we reviewed data obtained from three complementary sources; (1) general practitioner (GP) sentinel surveillance; (2) hospital discharge data from paediatric hospitals; and (3) laboratory based surveillance. The GP sentinel network is based on 500 physicians who electronically notify new cases of eight illnesses, including diarrhoea, each week. It was estimated that abour 3.3 million patients seek medical attention for diarrhoea from their GP each year, with a winter outbreak associated with an increased rate of isolation of rotavirus. A national system of hospital discharge diagnosis was used to estimate the burden of diarrhoeal morbidity in two paediatric wards in Tours, France. Between 1994 and 1996, 1164 patients under 15 y of age (9.7% of all admissions) were dehydrated and 52% were under 1 y old. Hospital admissions had a seasonal pattern similar to notifications from sentinel GP for children under 5 y old. A centralized laboratory surveillance network representing 17 of the 22 French regions describes a rotavirus outbreak each winter that is concomitant of outbreaks detected by the GP sentinel network and seen in hospitals. Most of the isolates (98%) identified through this surveillance system are among children under 5 y of age. All the data reviewed in this study indicate that the epidemiology of rotavirus diarrhoea in France fits well with what has been reported in other developed countries. □ Diarrhoea, general practice, hospitalization, rotavirus
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