| 依诺沙星注射液与替硝唑注射液的配伍稳定性考察 |
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| 引用本文： | 吴加娣,朱华,许建国,邵建屏. 依诺沙星注射液与替硝唑注射液的配伍稳定性考察[J]. 实用药物与临床, 2010, 13(5) |
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| 作者姓名： | 吴加娣 朱华 许建国 邵建屏 |
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| 作者单位： | 江苏省苏北人民医院药剂科,江苏,扬州,225001 |
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| 摘 要： | 目的考察葡萄糖酸依诺沙星注射液与替硝唑注射液配伍的稳定性。方法取依诺沙星注射液与替硝唑注射液配伍后的溶液,采用紫外分光光度法,测定其在25℃下6 h内不同时间的吸收度,计算依诺沙星、替硝唑配伍前后的含量。扫描紫外吸收图谱,观察溶液的外观,测定pH值。结果在25℃下,0～6 h内配伍液外观、pH值和紫外吸收图谱无明显变化,依诺沙星和替硝唑的含量无明显变化。结论依诺沙星注射液与替硝唑注射液在25℃下可配伍使用。
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| 关 键 词： | 依诺沙星 替硝唑 紫外分光光度法 配伍 |
Compatible stability of enoxacin injection combined with tinidazole injection |
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| WU Jia-di,ZHU Hua,XU Jian-guo,SHAO Jian-ping. Compatible stability of enoxacin injection combined with tinidazole injection[J]. Practical Pharmacy and Clinical Remedies, 2010, 13(5) |
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| Authors: | WU Jia-di ZHU Hua XU Jian-guo SHAO Jian-ping |
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| Abstract: | Objective To evaluate the stability of enoxacin gluconate injection combined with tinidazole injection.Methods Enoxacin gluconate injection was compatible with tinidazole injection,the absorbance of the solution in different time were determined at room temperature by UV spectrophotometry within 6 h.The color of solution was observed,and the pH value was determined.Results No significant change was found within 6 h.Conclusion Enoxacin gluconate injection could be compatible with tinidazole injection at room temperature. |
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| Keywords: | Enoxacin Tinidazole Ultraviolet spectrophotometry Compatibility |
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