Heart sensitivity to electrolyte composition of perfusion solution of rats after severe brain injury |
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| Authors: | V. V. Rusakov V. T. Dolgikh |
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| Affiliation: | (1) Department of Pathophysiology with Clinical Pathophysiology Course, Omsk State Medical Academy, Russia |
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| Abstract: | The in vitro model of isovolumic beating heart revealed enhanced sensitivity of the hearts from rats survived severe brain injury to concentration of Ca2+, Na+, and H+ ions in the perfusion solution. Inhibition of myocardial contractile function after trauma was accompanied by destruction signs in cardiomyocyte sarcolemma and mitochondrial dysfunction. __________ Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 141, No. 6, pp. 639–642, June, 2006 |
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| Keywords: | brain injury heart functional and metabolic disturbances |
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