| 阴脱汤对失血性休克家兔血浆内皮素、肿瘤坏死因子及一氧化氮含量的影响 |
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| 引用本文： | 赵丽红,赵锦程,李怀荆,李永毅,张建华. 阴脱汤对失血性休克家兔血浆内皮素、肿瘤坏死因子及一氧化氮含量的影响[J]. 黑龙江医药科学, 2005, 28(2): 14-15 |
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| 作者姓名： | 赵丽红 赵锦程 李怀荆 李永毅 张建华 |
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| 作者单位： | 1. 黑龙江省林业卫生学校,黑龙江,佳木斯,154007
2. 佳木斯大学药理教研室,黑龙江,佳木斯,154007 |
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| 摘 要： | 目的和方法:观察阴脱汤对失血性休克家兔休克前后血浆内皮素(ET)、肿瘤坏死因子(TNF)、一氧化氮(NO)含量及一氧化氮合酶(NOS)活性的影响,探讨阴脱汤对失血性休克的治疗作用。结果:阴脱汤能明显降低失血性休克家兔血浆ET、TNF、NO水平及NOS活力的升高(P <0 .0 5 )。结论:阴脱汤(YTT)可通过调节ET、TNF、NO水平及NOS活力等作用治疗失血性休克
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| 关 键 词： | 阴脱汤 内皮素 肿瘤坏死因 β-内啡肽 一氧化氮 休克 失血性 |
| 文章编号： | 1008-0104(2005)02-0014-02 |
| 修稿时间： | 2005-03-15 |
Effects of Yintuotang on the endothelin,tumor necrosis factorand nitric oxidele level in hemorrhagic shock in rabbits |
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| ZHAO Li-hong,ZHAO Jin-cheng,LI Huai-jing,LI Yong-yi,ZHANG Jian-hua. Effects of Yintuotang on the endothelin,tumor necrosis factorand nitric oxidele level in hemorrhagic shock in rabbits[J]. Heilongjiang Medicine and Pharmacy, 2005, 28(2): 14-15 |
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| Authors: | ZHAO Li-hong ZHAO Jin-cheng LI Huai-jing LI Yong-yi ZHANG Jian-hua |
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| Affiliation: | ZHAO Li-hong1,ZHAO Jin-cheng2,LI Huai-jing2,LI Yong-yi2,ZHANG Jian-hua2 |
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| Abstract: | Aim and Methods:To investigate the role of Yintuot an g(YTT) in the treatment in hemorrhagic shock in rabbits, the concentrations of e ndothelin(ET),tumor necrosis factor(TNF) and nitric oxidele (NO)level,and the a ctivity of nitric oxide synthase(NOS) in plasma were respectively tested by diff erent biochemical assays in hemorrhagic shock rabbits. Results:The YTT can obviously decrease the plasma ET, TNF, NO level and NOS activity(P<0. 05) in hemorrhagic shock rabbits. Conclusion: The YTT has better treatment value in hemorrhagic shock by improving the levels of ET, TNF and NO in plasma. |
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| Keywords: | Yintuotang endothelin tumor necrosis factor nitri c oxidele shock hemorrhagic |
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